Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 10785
TargetSigma intracellular receptor 2(Human)
Medisynergics

US Patent
LigandPNGBDBM497388(US11007200, Example 4a | US11426411, Example 4a)
Affinity DataKi:  15.5nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Medisynergics

US Patent
LigandPNGBDBM497384(US11007200, Example 2a | US11426411, Example 2a)
Affinity DataKi:  17.3nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Medisynergics

US Patent
LigandPNGBDBM497386(US11007200, Example 3a | US11426411, Example 3a)
Affinity DataKi:  18nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Medisynergics

US Patent
LigandPNGBDBM497386(US11007200, Example 3a | US11426411, Example 3a)
Affinity DataKi:  35.4nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Medisynergics

US Patent
LigandPNGBDBM568457(US11426411, Example 2b)
Affinity DataKi:  37.2nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Medisynergics

US Patent
LigandPNGBDBM497384(US11007200, Example 2a | US11426411, Example 2a)
Affinity DataKi:  59.8nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Medisynergics

US Patent
LigandPNGBDBM497390(US11007200, Example 13a | US11426411, Example 13a)
Affinity DataKi:  70nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Medisynergics

US Patent
LigandPNGBDBM497388(US11007200, Example 4a | US11426411, Example 4a)
Affinity DataKi:  97.2nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Medisynergics

US Patent
LigandPNGBDBM497390(US11007200, Example 13a | US11426411, Example 13a)
Affinity DataKi:  98nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Medisynergics

US Patent
LigandPNGBDBM497392(US11007200, Example 13b | US11426411, Example 13b)
Affinity DataKi:  146nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Medisynergics

US Patent
LigandPNGBDBM497387(US11007200, Example 3b | US11426411, Example 3b)
Affinity DataKi:  217nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Medisynergics

US Patent
LigandPNGBDBM568457(US11426411, Example 2b)
Affinity DataKi:  305nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Medisynergics

US Patent
LigandPNGBDBM497389(US11007200, Example 4b | US11426411, Example 4b)
Affinity DataKi:  426nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Medisynergics

US Patent
LigandPNGBDBM497392(US11007200, Example 13b | US11426411, Example 13b)
Affinity DataKi:  435nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma intracellular receptor 2(Human)
Medisynergics

US Patent
LigandPNGBDBM497387(US11007200, Example 3b | US11426411, Example 3b)
Affinity DataKi:  675nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Medisynergics

US Patent
LigandPNGBDBM497389(US11007200, Example 4b | US11426411, Example 4b)
Affinity DataKi:  697nMAssay Description:Ki determinations were generously provided by the National Institute of Mental Health's Psychoactive Drug Screening Program (PDSP).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent