Compile Data Set for Download or QSAR
Report error Found 67 Enz. Inhib. hit(s) with all data for entry = 10862
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575368BDBM575368(US11459336, Example 3 | 5-[[6-[3-(Difluoromethyl)-...)
Affinity DataIC50: 13nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575400BDBM575400(US11459336, Example 35 | 3-[[6-[4-Chloro-3-(difluo...)
Affinity DataIC50: 13nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575403BDBM575403(US11459336, Example 38 | 5-[[6-[3-(1,1-Difluoroeth...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575387BDBM575387(US11459336, Example 22 | 3-[[6-[3-(Difluoromethoxy...)
Affinity DataIC50: 17nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575402BDBM575402(US11459336, Example 37 | 3-[[6-[4-Chloro-3-(difluo...)
Affinity DataIC50: 18nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575394BDBM575394(US11459336, Example 29 | 5-[[6-[4-Chloro-3-(difluo...)
Affinity DataIC50: 19nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575381BDBM575381(US11459336, Example 16 | 5-[[6-[3-(Difluoromethoxy...)
Affinity DataIC50: 19nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575396BDBM575396(US11459336, Example 31 | (5R)-3-[[6-[4-Chloro-3-(d...)
Affinity DataIC50: 20nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575397BDBM575397(US11459336, Example 32 | (5S)-3-[[6-[4-Chloro-3-(d...)
Affinity DataIC50: 20nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575386BDBM575386(US11459336, Example 21 | (5S)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 20nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575398BDBM575398(US11459336, Example 33 | (4R)-3-[[6-[4-Chloro-3-(d...)
Affinity DataIC50: 21nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575385BDBM575385(US11459336, Example 20 | (5R)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 29nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575370BDBM575370(US11459336, Example 5 | (5R)-3-[[6-[3-(Difluoromet...)
Affinity DataIC50: 29nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575375BDBM575375(US11459336, Example 10 | 5-[[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 37nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575405BDBM575405(US11459336, Example 40 | (5R)-3-[[6-[3-(1,1-Difluo...)
Affinity DataIC50: 39nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575393BDBM575393(US11459336, Example 28 | 3-[[6-[3-(Difluoromethoxy...)
Affinity DataIC50: 39nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575383BDBM575383(US11459336, Example 18 | (4R)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 44nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575378BDBM575378(US11459336, Example 13 | (5R)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 45nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575392BDBM575392(US11459336, Example 27 | (5S)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 48nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575414BDBM575414(US11459336, Example 49 | 6-[[6-[3-(Difluoromethoxy...)
Affinity DataIC50: 48nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575415BDBM575415(US11459336, Example 50 | 6-[[6-[4-Chloro-3-(difluo...)
Affinity DataIC50: 49nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575379BDBM575379(US11459336, Example 14 | (5S)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 50nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575391BDBM575391(US11459336, Example 26 | (5R)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 52nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575371BDBM575371(US11459336, Example 6 | (5S)-3-[[6-[3-(Difluoromet...)
Affinity DataIC50: 60nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575416BDBM575416(US11459336, Example 52 | 6-[[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 61nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575374BDBM575374(US11459336, Example 9 | 3-[[6-[3-(Difluoromethyl)-...)
Affinity DataIC50: 65nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575380BDBM575380(US11459336, Example 15 | 3-[[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 65nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575388BDBM575388(US11459336, Example 23 | 5-[[6-[3-(Difluoromethoxy...)
Affinity DataIC50: 66nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575367BDBM575367(US11459336, Example 2 | 3-[[6-[3-(Difluoromethoxy)...)
Affinity DataIC50: 73nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575418BDBM575418(US11459336, Example 54 | 6-[[6-[3-(Difluoromethoxy...)
Affinity DataIC50: 74nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575389BDBM575389(US11459336, Example 24 | (4R)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 78nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575399BDBM575399(US11459336, Example 34 | (4S)-3-[[6-[4-Chloro-3-(d...)
Affinity DataIC50: 86nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575417BDBM575417(US11459336, Example 53 | 6-[[6-[3-(Difluoromethyl)...)
Affinity DataIC50: 102nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575407BDBM575407(US11459336, Example 42 | 3-[[6-[3-(1,1-Difluoroeth...)
Affinity DataIC50: 105nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575401BDBM575401(US11459336, Example 36 | 5-[[6-[4-Chloro-3-(difluo...)
Affinity DataIC50: 113nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575413BDBM575413(US11459336, Example 48 | 6-[[6-[3-(1,1-Difluoroeth...)
Affinity DataIC50: 124nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575410BDBM575410(US11459336, Example 45 | 3-[[6-[3-(1,1-Difluoroeth...)
Affinity DataIC50: 127nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575430BDBM575430(US11459336, Example 66 | (R/S)-3-[[6-[3-(Difluorom...)
Affinity DataIC50: 141nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575411BDBM575411(US11459336, Example 46 | (4R)-3-[[6-[3-(1,1-Difluo...)
Affinity DataIC50: 166nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575406BDBM575406(US11459336, Example 41 | (5S)-3-[[6-[3-(1,1-Difluo...)
Affinity DataIC50: 167nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575376BDBM575376(US11459336, Example 11 | (4R)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 192nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575217BDBM575217(US11459336, Example 1 | 3-[[6-[3-(Difluoromethyl)-...)
Affinity DataIC50: 195nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575408BDBM575408(US11459336, Example 43 | 5-[[6-[3-(1,1-Difluoroeth...)
Affinity DataIC50: 203nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575372BDBM575372(US11459336, Example 7 | (4R)-3-[[6-[3-(Difluoromet...)
Affinity DataIC50: 288nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575384BDBM575384(US11459336, Example 19 | (4S)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 291nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575390BDBM575390(US11459336, Example 25 | (4S)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 388nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575431BDBM575431(US11459336, Example 67 | 64[6-[4-Chloro-3-(difluor...)
Affinity DataIC50: 530nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575432BDBM575432(US11459336, Example 68 | 64[6-[4-Chloro-3-(difluor...)
Affinity DataIC50: 599nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575377BDBM575377(US11459336, Example 12 | (4S)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 605nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 575412BDBM575412(US11459336, Example 47 | (4S)-3-[[6-[3-(1,1-Difluo...)
Affinity DataIC50: 624nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

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