Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 10871
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575844(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-1-methyl-4-...)
Affinity DataIC50:  0.300nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575868(4-((6-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-1-methy...)
Affinity DataIC50:  0.340nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575845((S)-2-(6-(3,5-dimethylisoxazol-4-yl)-4-((3-fluorop...)
Affinity DataIC50:  0.350nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575867((S)-2-(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-4-((...)
Affinity DataIC50:  0.400nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575781((S)-2-(6-(3,5-dimethylisoxazol-4-yl)-1-methyl-4-(p...)
Affinity DataIC50:  0.480nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575853((S)-2-(6-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-1-me...)
Affinity DataIC50:  0.490nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575852(2-(4-((3-Fluoropyridin-2-yl)(tetrahydro-2H-pyran-4...)
Affinity DataIC50:  0.540nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575846(6-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-N,1-dimethy...)
Affinity DataIC50:  0.550nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575849(2-(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-1-methyl...)
Affinity DataIC50:  0.570nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575851(2-(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-1-methyl...)
Affinity DataIC50:  0.590nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575869(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-N,N,1-trime...)
Affinity DataIC50:  0.610nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575847(2-(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-1-methyl...)
Affinity DataIC50:  0.660nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575856(2-(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-4-((3-me...)
Affinity DataIC50:  0.680nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575850(3-(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-1-methyl...)
Affinity DataIC50:  0.790nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575854(2-(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-4-((3-fl...)
Affinity DataIC50:  0.880nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575855((S)-2-(6-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-4-((...)
Affinity DataIC50:  0.970nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575859(2-(6-(3,5-dimethylisoxazol-4-yl)-1-methyl-4-((tetr...)
Affinity DataIC50:  0.990nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575848(2-(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-1-methyl...)
Affinity DataIC50:  1.10nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575863(2-(6-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-1-methyl...)
Affinity DataIC50:  1.30nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575865(2-(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-1-methyl...)
Affinity DataIC50:  1.60nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575860((S)—N-(6-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)...)
Affinity DataIC50:  1.90nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575861(2-(6-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-1-methyl...)
Affinity DataIC50:  2.20nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575862((R)-2-(6-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-4-((...)
Affinity DataIC50:  3nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575864((R)-2-(6-(3,5-dimethylisoxazol-4-yl)-4-((3-fluorop...)
Affinity DataIC50:  4.60nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575866(6-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-1-methyl-3-...)
Affinity DataIC50:  4.67nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575857(2-(6-(3,5-dimethylisoxazol-4-yl)-1-methyl-4-((3-me...)
Affinity DataIC50:  12nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM575858(2-(6-(1,4-Dimethyl-1H-1,2,3-triazol-5-yl)-4-(1-(4-...)
Affinity DataIC50:  17nMAssay Description:Briefly, 20 nL of compounds were transferred to the 384-well plate by EchoŽ 550 liquid handler (Labcyte, USA), then 5 μL of BRD4(BD1) (Reaction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent