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maximum 50k data
Found 45 Enz. Inhib. hit(s) with all data for entry = 10925
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578777(US11479550, Example 18-5(2))
Affinity DataKi:  120nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578749(US11479550, Example 3-9(2))
Affinity DataKi:  410nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578757(US11479550, Example 8-3(2))
Affinity DataKi:  1.50E+3nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578759(US11479550, Example 8-13(2))
Affinity DataKi:  1.60E+3nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578769(US11479550, Example 11-15(2) | US11479550, Example...)
Affinity DataKi:  2.30E+3nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578739(4-{4-[(1,1-dioxide-1,2-thiazolidin-2-yl)methyl]-2-...)
Affinity DataKi: >1.00E+4nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578769(US11479550, Example 11-15(2) | US11479550, Example...)
Affinity DataIC50:  0.570nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578749(US11479550, Example 3-9(2))
Affinity DataIC50:  0.700nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578774(4-[2-({2-[3-methyl-6-(methylcarbamoyl)-1H-indol-1-...)
Affinity DataIC50:  0.790nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578746(US11479550, Example 3-3(2))
Affinity DataIC50:  0.900nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578743(US11479550, Example 2-6(2))
Affinity DataIC50:  1.20nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578764(US11479550, Example 11-1(2))
Affinity DataIC50:  1.30nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578751(US11479550, Example 3-20(2))
Affinity DataIC50:  1.40nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578756(US11479550, Example 7-3(2))
Affinity DataIC50:  1.5nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578766(US11479550, Example 11-7(2))
Affinity DataIC50:  1.60nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578773(US11479550, Example 12-1(2))
Affinity DataIC50:  1.60nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578748(US11479550, Example 3-7(2))
Affinity DataIC50:  1.70nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578745(US11479550, Example 2-27(4))
Affinity DataIC50:  1.80nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578769(US11479550, Example 11-15(2) | US11479550, Example...)
Affinity DataIC50:  1.90nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578768(US11479550, Example 11-11(2))
Affinity DataIC50:  2nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578747(US11479550, Example 3-5(2))
Affinity DataIC50:  2.10nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578762(US11479550, Example 9-5(2))
Affinity DataIC50:  2.20nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578752(US11479550, Example 4-1(2))
Affinity DataIC50:  2.5nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578754(US11479550, Example 6-5(1))
Affinity DataIC50:  2.70nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578753(US11479550, Example 4-8(2))
Affinity DataIC50:  2.70nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578765(US11479550, Example 11-3(2))
Affinity DataIC50:  2.70nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578777(US11479550, Example 18-5(2))
Affinity DataIC50:  3.20nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578758(US11479550, Example 8-9(2))
Affinity DataIC50:  3.30nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578741(4-{4-[(4-chloro-1H-pyrazol-1-yl)methyl]-2-({2-[3-m...)
Affinity DataIC50:  3.30nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578755(US11479550, Example 7-1(2))
Affinity DataIC50:  3.30nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578763(US11479550, Example 10-1(2))
Affinity DataIC50:  3.70nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578767(4-[2-({2-[6-(benzylcarbamoyl)-3-methyl-1H-indol-1-...)
Affinity DataIC50:  4nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578750(US11479550, Example 3-11(2))
Affinity DataIC50:  4.60nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578761(US11479550, Example 9-1(2))
Affinity DataIC50:  4.60nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578757(US11479550, Example 8-3(2))
Affinity DataIC50:  4.80nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578740(4-[4-{[(2,6-dimethyl-4-pyridinyl)oxy]methyl}-2-({2...)
Affinity DataIC50:  4.90nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578744(4-[4-(5,6-dihydrocyclopenta[c]pyrazol-2(4H)-ylmeth...)
Affinity DataIC50:  5.5nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578776(4-{4-[hydroxy(1-methyl-1H-pyrazol-4-yl)methyl]-2-(...)
Affinity DataIC50:  6.20nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578759(US11479550, Example 8-13(2))
Affinity DataIC50:  6.30nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578775(US11479550, Example 15-1(2))
Affinity DataIC50:  6.40nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578770(US11479550, Example 11-23(2))
Affinity DataIC50:  6.5nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578760(US11479550, Example 8-17(2))
Affinity DataIC50:  8.60nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578772(US11479550, Example 11-30(2))
Affinity DataIC50:  12nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578739(4-{4-[(1,1-dioxide-1,2-thiazolidin-2-yl)methyl]-2-...)
Affinity DataIC50:  27nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM578742(4-{4-[(1,1-dioxide-1,2-thiazinan-2-yl)methyl]-2-({...)
Affinity DataIC50:  39nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent