Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 10989
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582048(US11518761, Example 107)
Affinity DataIC50: 6.16nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582049(US11518761, Example 135)
Affinity DataIC50: 7.05nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582050(US11518761, Example 121)
Affinity DataIC50: 7.41nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582051(US11518761, Example 42)
Affinity DataIC50: 8.37nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582044(US11518761, Example 6)
Affinity DataIC50: 8.70nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582052(US11518761, Example 124)
Affinity DataIC50: 8.87nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582053(US11518761, Example 109)
Affinity DataIC50: 9.79nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582054(US11518761, Example 111)
Affinity DataIC50: 10.2nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582076(US11518761, Example 157)
Affinity DataIC50: 11nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582077(US11518761, Example 158)
Affinity DataIC50: 11.4nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582055(US11518761, Example 131)
Affinity DataIC50: 11.4nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582056(US11518761, Example 154)
Affinity DataIC50: 11.8nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)
Affinity DataIC50: 13nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582079(US11518761, Example 160)
Affinity DataIC50: 13.6nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582080(US11518761, Example 161)
Affinity DataIC50: 14.2nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582057(US11518761, Example 112)
Affinity DataIC50: 14.6nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582059(US11518761, Example 116)
Affinity DataIC50: 15.4nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582058(US11518761, Example 130)
Affinity DataIC50: 15.4nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)
Affinity DataIC50: 16.5nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582038(US11518761, Example 23)
Affinity DataIC50: 17.2nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582081(US11518761, Example 175 | US11518761, Example 162)
Affinity DataIC50: 17.4nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582081(US11518761, Example 175 | US11518761, Example 162)
Affinity DataIC50: 17.4nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582082(US11518761, Example 163)
Affinity DataIC50: 18nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582061(US11518761, Example 127)
Affinity DataIC50: 18.4nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582062(US11518761, Example 54)
Affinity DataIC50: 18.9nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582063(US11518761, Example 83)
Affinity DataIC50: 20.6nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582064(US11518761, Example 78)
Affinity DataIC50: 21.7nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582043(US11518761, Example 5)
Affinity DataIC50: 25.3nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582046(US11518761, Example 17)
Affinity DataIC50: 25.4nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582065(US11518761, Example 88)
Affinity DataIC50: 25.4nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582039(US11518761, Example 9)
Affinity DataIC50: 26.3nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582066(US11518761, Example 113)
Affinity DataIC50: 26.5nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582067(US11518761, Example 152)
Affinity DataIC50: 27.3nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582083(US11518761, Example 164)
Affinity DataIC50: 28.3nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582068(US11518761, Example 128)
Affinity DataIC50: 28.3nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582069(US11518761, Example 132)
Affinity DataIC50: 28.4nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582085(US11518761, Example 166)
Affinity DataIC50: 28.9nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582084(US11518761, Example 165)
Affinity DataIC50: 28.9nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582070(US11518761, Example 86)
Affinity DataIC50: 29.6nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582071(US11518761, Example 151)
Affinity DataIC50: 31.3nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582072(US11518761, Example 153)
Affinity DataIC50: 33.8nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582073(US11518761, Example 125)
Affinity DataIC50: 36nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582086(US11518761, Example 167)
Affinity DataIC50: 36.4nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582087(US11518761, Example 168)
Affinity DataIC50: 37.1nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582074(US11518761, Example 38)
Affinity DataIC50: 37.6nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582088(US11518761, Example 169)
Affinity DataIC50: 37.7nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582075(US11518761, Example 155)
Affinity DataIC50: 38nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582089(US11518761, Example 170)
Affinity DataIC50: 38.6nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582090(US11518761, Example 171)
Affinity DataIC50: 41.1nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM582091(US11518761, Example 172)
Affinity DataIC50: 45.9nMAssay Description:Certain of the compounds prepared as described above were assayed to determine their IC50 for inhibition of T. gondii CDPK1 (tgCDPK1). At least three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
US Patent

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