Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 10998
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582516(US11524956, Example 1)
Affinity DataIC50: <100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582516(US11524956, Example 1)
Affinity DataIC50: <100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582537((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-((S)-...)
Affinity DataIC50: <100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582537((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-((S)-...)
Affinity DataIC50: <100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582539((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-((R)-...)
Affinity DataIC50: <100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582539((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-((R)-...)
Affinity DataIC50: <100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582543((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-((1S,...)
Affinity DataIC50: <100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582540((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-((1R,...)
Affinity DataIC50: <100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582541((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-(3-ox...)
Affinity DataIC50: <100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582541((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-(3-ox...)
Affinity DataIC50: <100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582542((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-((1R,...)
Affinity DataIC50: <100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582542((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-((1R,...)
Affinity DataIC50: <100nMAssay Description:The assay is performed similarly to the kinase assay for ErbB2 as described above, except ErbB2 kinase protein is used instead of EGFR kinase protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582543((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-((1S,...)
Affinity DataIC50: <100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Newgen Therapeutics

US Patent
LigandPNGBDBM582540((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-((1R,...)
Affinity DataIC50: <100nMAssay Description:The assay is performed in a Black 384-well plate (available from Corning). EGFR kinase (is diluted in TR-FRET Dilution Buffer (PV3189, InVitrogen) at...More data for this Ligand-Target Pair
In DepthDetails US Patent