Compile Data Set for Download or QSAR
Report error Found 289 Enz. Inhib. hit(s) with all data for entry = 11045
TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587951(US11535621, Example 200)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587822(US11535621, Example 81)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587825(US11535621, Example 84)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587826(US11535621, Example 85)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587823(US11535621, Example 82)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587824(US11535621, Example 83)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587829(US11535621, Example 88)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587830(US11535621, Example 89)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587956(US11535621, Example 205)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587827(US11535621, Example 86)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587828(US11535621, Example 87)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587962(US11535621, Example 211)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587833(US11535621, Example 92)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587963(US11535621, Example 212)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587831(US11535621, Example 90)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587961(US11535621, Example 210)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587832(US11535621, Example 91)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587934(US11535621, Example 184)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587935(US11535621, Example 185)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587932(US11535621, Example 182)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587933(US11535621, Example 183)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587803(US11535621, Example 63)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587942(N-((1S,4r)-4-((S)-1-hydroxyethyl)cyclohexyl)-5-(1H...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587943(N-((1S,4r)-4-((S)-1-hydroxyethyl)cyclohexyl)-5-(1H...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587940(US11535621, Example 190)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587817(US11535621, Example 77)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587815(US11535621, Example 75)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587982(US11535621, Example 231)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587980(US11535621, Example 229)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587987(US11535621, Example 236)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587855(N-((1r,4r)-4-(acetamidomethyl)cyclohexyl)-2-(1H-im...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587990(US11535621, Example 239 | US11535621, Example 247)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587862(N-((1s,4s)-4-hydroxy-4-(trifluoromethyl)cyclohexyl...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587988(US11535621, Example 237)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587859(US11535621, Example 118)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587989(US11535621, Example 238)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587866(US11535621, Example 122)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587865(2-(1H-imidazol-1-yl)-N-((1r,4r)-4-(trifluoromethyl...)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587966(US11535621, Example 215)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587837(US11535621, Example 96)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587835(US11535621, Example 94)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587965(US11535621, Example 214)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587970(US11535621, Example 219)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587841(US11535621, Example 100)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587968(US11535621, Example 217)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587839(US11535621, Example 98)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587840(US11535621, Example 99)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587845(US11535621, Example 104)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587975(US11535621, Example 224)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587979(US11535621, Example 228)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

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