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Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 11050
TargetCoagulation factor XI(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM588063(US11541049, Example 5)
Affinity DataIC50: 0.160nMAssay Description:Reagents:Enzyme: human coagulation factor XIa; manufacturer: Haemtech;Substrate: Boc-Ile-Glu-Gly-Arg-AMC Acetate salt; manufacturer: Bachem;Reaction ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM588060(US11541049, Example 2)
Affinity DataIC50: 0.210nMAssay Description:Reagents:Enzyme: human coagulation factor XIa; manufacturer: Haemtech;Substrate: Boc-Ile-Glu-Gly-Arg-AMC Acetate salt; manufacturer: Bachem;Reaction ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM588061(4-((S)-5-(1-((S)-2-amino-4-carboxybutanoyl)-1,2,3,...)
Affinity DataIC50: 0.290nMAssay Description:Reagents:Enzyme: human coagulation factor XIa; manufacturer: Haemtech;Substrate: Boc-Ile-Glu-Gly-Arg-AMC Acetate salt; manufacturer: Bachem;Reaction ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM588059(4-((S)-5-(1-((S)-2-amino-3-methylbutanoyl)-1,2,3,6...)
Affinity DataIC50: 0.330nMAssay Description:Reagents:Enzyme: human coagulation factor XIa; manufacturer: Haemtech;Substrate: Boc-Ile-Glu-Gly-Arg-AMC Acetate salt; manufacturer: Bachem;Reaction ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM588062(4-((S)-5-(1-((S)-2-aminopropanoyl)-1,2,3,6-tetrahy...)
Affinity DataIC50: 0.850nMAssay Description:Reagents:Enzyme: human coagulation factor XIa; manufacturer: Haemtech;Substrate: Boc-Ile-Glu-Gly-Arg-AMC Acetate salt; manufacturer: Bachem;Reaction ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetCoagulation factor VII(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM588063(US11541049, Example 5)
Affinity DataIC50: 1.00E+4nMAssay Description:The test compounds were dissolved in assay buffer (50 mM Hepes, 150 mM NaCl, 5 mM CaCl2, pH 7.4) at a final concentration of 10 μM and 1 μM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetCoagulation factor X(Human)
Sichuan Kelun-Biotech Biopharmaceutical

US Patent
LigandPNGBDBM588063(US11541049, Example 5)
Affinity DataIC50: 1.00E+4nMAssay Description:The test compounds were dissolved in assay buffer (50 mM Tris, 150 mM NaCl, 10 mM CaCl2, 0.05% Brij35, pH 7.5) at a final concentration of 10 μM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent