Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 11057
TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588181(US11542251, Compound TL1)
Affinity DataIC50: 3nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588181(US11542251, Compound TL1)
Affinity DataIC50: 7nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588182(US11542251, Compound TL2)
Affinity DataIC50: 9nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588177(US11542251, Compound 1)
Affinity DataIC50: 16nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588179(US11542251, Compound 3)
Affinity DataIC50: 18nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588179(US11542251, Compound 3)
Affinity DataIC50: 40nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588178(US11542251, Compound 2)
Affinity DataIC50: 42nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588177(US11542251, Compound 1)
Affinity DataIC50: 43nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588178(US11542251, Compound 2)
Affinity DataIC50: 44nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588180(US11542251, Compound 4)
Affinity DataIC50: 142nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588180(US11542251, Compound 4)
Affinity DataIC50: 212nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM588182(US11542251, Compound TL2)
Affinity DataIC50: 1.00E+4nMAssay Description:The IRAK1 and IRAK 4 IC50 values for various compounds disclosed herein generated from an Adapta kinase assay format, and a Z′-LYTE kinases ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent