Compile Data Set for Download or QSAR
Report error Found 238 Enz. Inhib. hit(s) with all data for entry = 11069
TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585871BDBM585871(US11530237, Compound 29 | US11542297, Compound 29)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 588689BDBM588689(US11542297, Compound 104)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585870BDBM585870(US11530237, Compound 28 | US11542297, Compound 28)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 588823BDBM588823(US11542297, Compound 248)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 586067BDBM586067(US11530237, Compound 248 | US11542297, Compound 24...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585939BDBM585939(US11530237, Compound 128 | US11530237, Compound 11...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 588629BDBM588629(US11542297, Compound 32)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585877BDBM585877(US11530237, Compound 35 | US11542297, Compound 35)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585878BDBM585878(US11530237, Compound 36 | US11542297, Compound 36)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 586009BDBM586009(US11530237, Compound 185 | US11542297, Compound 18...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585946BDBM585946(US11530237, Compound 117 | US11542297, Compound 11...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585882BDBM585882(US11530237, Compound 40 | US11542297, Compound 40)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585919BDBM585919(US11530237, Compound 78 | US11542297, Compound 78)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585855BDBM585855(US11530237, Compound 11 | US11542297, Compound 11)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585856BDBM585856(US11530237, Compound 12 | US11542297, Compound 12)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585854BDBM585854(US11530237, Compound 10 | US11542297, Compound 10)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585859BDBM585859(US11530237, Compound 15 | US11542297, Compound 15)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585860BDBM585860(US11530237, Compound 16 | US11542297, Compound 16)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 588678BDBM588678(US11542297, Compound 86)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585858BDBM585858(US11530237, Compound 14 | US11542297, Compound 14)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585863BDBM585863(US11530237, Compound 19 | US11542297, Compound 19)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585864BDBM585864(US11530237, Compound 21 | US11542297, Compound 21)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585990BDBM585990(US11530237, Compound 165 | US11542297, Compound 16...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585862BDBM585862(US11530237, Compound 18 | US11542297, Compound 18)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585867BDBM585867(US11530237, Compound 24 | US11542297, Compound 24)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 588688BDBM588688(US11542297, Compound 103)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585868BDBM585868(US11530237, Compound 26 | US11542297, Compound 26)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585865BDBM585865(US11530237, Compound 22 | US11542297, Compound 22)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585866BDBM585866(US11530237, Compound 23 | US11542297, Compound 23)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 588727BDBM588727(US11542297, Compound 146)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585915BDBM585915(US11530237, Compound 74 | US11542297, Compound 74)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585951BDBM585951(US11530237, Compound 124 | US11542297, Compound 12...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 586015BDBM586015(US11530237, Compound 191 | US11542297, Compound 19...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 586079BDBM586079(US11530237, Compound 260 | US11542297, Compound 26...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 586078BDBM586078(US11530237, Compound 259 | US11542297, Compound 25...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585886BDBM585886(US11530237, Compound 45 | US11542297, Compound 45)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585939BDBM585939(US11530237, Compound 128 | US11530237, Compound 11...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 588646BDBM588646(US11542297, Compound 50)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585959BDBM585959(US11530237, Compound 133 | US11542297, Compound 13...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585895BDBM585895(US11530237, Compound 54 | US11542297, Compound 54)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585894BDBM585894(US11530237, Compound 53 | US11542297, Compound 53)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 586026BDBM586026(US11530237, Compound 204 | US11542297, Compound 20...)
Affinity DataIC50: 10nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 588692BDBM588692(US11542297, Compound 107)
Affinity DataIC50: 30nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 588690BDBM588690(US11542297, Compound 105)
Affinity DataIC50: 30nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585939BDBM585939(US11530237, Compound 128 | US11530237, Compound 11...)
Affinity DataIC50: 30nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585937BDBM585937(US11530237, Compound 108 | US11542297, Compound 10...)
Affinity DataIC50: 30nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 588699BDBM588699(US11542297, Compound 114)
Affinity DataIC50: 30nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585944BDBM585944(US11530237, Compound 115 | US11542297, Compound 11...)
Affinity DataIC50: 30nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585941BDBM585941(US11530237, Compound 112 | US11542297, Compound 11...)
Affinity DataIC50: 30nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit gamma-1(Rat)
Sage Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 585942BDBM585942(US11530237, Compound 113 | US11542297, Compound 11...)
Affinity DataIC50: 30nMAssay Description:Briefly, cortices are rapidly removed following decapitation of carbon dioxide-anesthetized Sprague-Dawley rats (200-250 g). The cortices are homogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

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