Compile Data Set for Download or QSAR
maximum 50k data
Found 468 Enz. Inhib. hit(s) with all data for entry = 11123
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592760(2-chloro-N-(8-cyano-8- azabicyclo[3.2.1]octan-2-yl...)
Affinity DataIC50:  10nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592741((3S)-6-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[...)
Affinity DataIC50:  17nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592645((3S)-6-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[...)
Affinity DataIC50:  20nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592753(1-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2...)
Affinity DataIC50:  22nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592927((3S)-1-(3-chloro-5-methylphenyl)-N- ((1R.2R,4S)-7-...)
Affinity DataIC50:  25nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592951(US11572374, Example 12-2-3)
Affinity DataIC50:  25nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592826(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  26nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592779((3E)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]hep...)
Affinity DataIC50:  26nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592654(6-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  26nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592735(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  27nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592861(2-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  27nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592819(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  28nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592920((3S)-1-(3-chloro-6-(trifluoromethyl)-2- pyridinyl)...)
Affinity DataIC50:  29nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592926((3S)-1-(3-chloro-5-(trifluoromethyl)phenyl)- N-((1...)
Affinity DataIC50:  29nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592827(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  30nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592697(2-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  31nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592775((3E)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]hep...)
Affinity DataIC50:  34nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592924((3S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]hep...)
Affinity DataIC50:  37nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592755(2-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  37nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592781((2E)-3-(5-chloro-1-benzothiophen-3-yl)-N- ((1R,2R,...)
Affinity DataIC50:  38nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592839(N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2...)
Affinity DataIC50:  39nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592778((2E)-3-(5-chloro-1-ethyl-1H-indol-3-yl)-N- ((1R,2R...)
Affinity DataIC50:  40nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592837(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  41nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592782(3'-bromo-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  44nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592940((3S)-1-(3-chloro-5-cyanophenyl)-N-((1R,2R,4S)-7-cy...)
Affinity DataIC50:  44nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592714(2-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  46nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592912((3S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]hep...)
Affinity DataIC50:  46nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592822(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  47nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592805((1S,4R,5S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2...)
Affinity DataIC50:  48nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592829(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  49nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592886(N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2...)
Affinity DataIC50:  50nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592968(N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2...)
Affinity DataIC50:  50nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592913((3S)-1-(5-chloro-2-cyanophenyl)-N- ((1R,2R,4S)-7-c...)
Affinity DataIC50:  54nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592777((3E)-4-(3-chlorophenyl)-N-((1R,2R,4S)-7- cyano-7-a...)
Affinity DataIC50:  54nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592937((3S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]hep...)
Affinity DataIC50:  54nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592816(3,3'-dichloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[...)
Affinity DataIC50:  55nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592818(3,4'-dichloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[...)
Affinity DataIC50:  55nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592765(N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2...)
Affinity DataIC50:  56nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592759(6-(((1-(4- bromophenyl)cyclopropyl)methyl)(meth- y...)
Affinity DataIC50:  57nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592808(6-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  57nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592880(N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2...)
Affinity DataIC50:  58nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592918((3S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]hep...)
Affinity DataIC50:  58nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592815(2',3-dichloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[...)
Affinity DataIC50:  60nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592674(2-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  61nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592694(3-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Affinity DataIC50:  62nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592947((1R,4R,5R)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2...)
Affinity DataIC50:  62nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592934((3S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]hep...)
Affinity DataIC50:  62nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592742(N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2...)
Affinity DataIC50:  64nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592764(N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2...)
Affinity DataIC50:  64nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30 [57-517](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM592944((3S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]hep...)
Affinity DataIC50:  64nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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