Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 11127
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM593006((S)-6-(2,2-difluorocyclopropane-1-carboxamido)-4-(...)
Affinity DataIC50:  4.90nMAssay Description:A binding buffer contains 20 mM Hepes pH 7.5, 150 mM NaCl, 10 mM MgCl, 0.015% Brij35, 2 mM DTT, 0.625 mM EGTA and 100 mM KF. The JH2 domain of TYK2 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM593006((S)-6-(2,2-difluorocyclopropane-1-carboxamido)-4-(...)
Affinity DataIC50:  5.40nMAssay Description:A binding buffer contains 20 mM Hepes pH 7.5, 150 mM NaCl, 10 mM MgCl, 0.015% Brij35, 2 mM DTT, 0.625 mM EGTA and 100 mM KF. The JH2 domain of TYK2 (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50:  5.5nMAssay Description:A binding buffer contains 20 mM Hepes pH 7.5, 150 mM NaCl, 10 mM MgCl, 0.015% Brij35, 2 mM DTT, 0.625 mM EGTA and 100 mM KF. The JH2 domain of TYK2 (...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50:  5.60nMAssay Description:A binding buffer contains 20 mM Hepes pH 7.5, 150 mM NaCl, 10 mM MgCl, 0.015% Brij35, 2 mM DTT, 0.625 mM EGTA and 100 mM KF. The JH2 domain of TYK2 (...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50:  5.70nMAssay Description:A binding buffer contains 20 mM Hepes pH 7.5, 150 mM NaCl, 10 mM MgCl, 0.015% Brij35, 2 mM DTT, 0.625 mM EGTA and 100 mM KF. The JH2 domain of TYK2 (...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50:  840nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT and 0.01% Brij35 from the kit; a human recombinant ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50:  2.10E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT, 10 nM SEB (Cisbio, Cat. No. 61SEBALB), 0.625 mM EG...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50:  2.20E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT and 0.01% Brij35 from the kit; a human recombinant ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50:  2.30E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT and 0.01% Brij35 from the kit; a human recombinant ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50:  2.30E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT and 0.01% Brij35 from the kit; a human recombinant ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50:  2.90E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT, 10 nM SEB (Cisbio, Cat. No. 61SEBALB), 0.625 mM EG...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50:  3.00E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT and 0.01% Brij35 from the kit; a human recombinant ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM593006((S)-6-(2,2-difluorocyclopropane-1-carboxamido)-4-(...)
Affinity DataIC50:  6.30E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT, 10 nM SEB (Cisbio, Cat. No. 61SEBALB), 0.625 mM EG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM593006((S)-6-(2,2-difluorocyclopropane-1-carboxamido)-4-(...)
Affinity DataIC50:  7.00E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT and 0.01% Brij35 from the kit; a human recombinant ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM593021((R)-6-(2,2-difluorocyclopropane-1-carboxamido)-4-(...)
Affinity DataIC50:  7.50E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT and 0.01% Brij35 from the kit; a human recombinant ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM593006((S)-6-(2,2-difluorocyclopropane-1-carboxamido)-4-(...)
Affinity DataIC50:  7.80E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT and 0.01% Brij35 from the kit; a human recombinant ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM593021((R)-6-(2,2-difluorocyclopropane-1-carboxamido)-4-(...)
Affinity DataIC50:  8.50E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT and 0.01% Brij35 from the kit; a human recombinant ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM593006((S)-6-(2,2-difluorocyclopropane-1-carboxamido)-4-(...)
Affinity DataIC50:  9.50E+3nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT, 10 nM SEB (Cisbio, Cat. No. 61SEBALB), 0.625 mM EG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM593021((R)-6-(2,2-difluorocyclopropane-1-carboxamido)-4-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT, 10 nM SEB (Cisbio, Cat. No. 61SEBALB), 0.625 mM EG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM593021((R)-6-(2,2-difluorocyclopropane-1-carboxamido)-4-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT, 10 nM SEB (Cisbio, Cat. No. 61SEBALB), 0.625 mM EG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50: >1.00E+4nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT, 10 nM SEB (Cisbio, Cat. No. 61SEBALB), 0.625 mM EG...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50: >1.00E+4nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT, 10 nM SEB (Cisbio, Cat. No. 61SEBALB), 0.625 mM EG...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM500288(US11021475, Example 52 | US11021475, Example 67 | ...)
Affinity DataIC50: >1.00E+4nMAssay Description:A reaction buffer containing the following components: an enzyme buffer (1×), 5 mM MgCl, 1 mM DTT, 10 nM SEB (Cisbio, Cat. No. 61SEBALB), 0.625 mM EG...More data for this Ligand-Target Pair