Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 11135
TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50548076BDBM50548076(CHEMBL4781133 | US11583532, Example 5.1)
Affinity DataIC50: 0.130nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593981BDBM593981(US11583532, Example 8.2)
Affinity DataIC50: 0.230nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 594010BDBM594010(6-{[5-Bromo-6-(3,3-difluoropyrrolidin-1-yl)pyridin...)
Affinity DataIC50: 0.25nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593980BDBM593980(6-{[5-Bromo-6-(3-fluoropropoxy)pyridin-2-yl]methyl...)
Affinity DataIC50: 0.270nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 594008BDBM594008(US11583532, Example 21.1 | US11583532, Example 23....)
Affinity DataIC50: 0.290nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593983BDBM593983(US11583532, Example 8.4)
Affinity DataIC50: 0.300nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593982BDBM593982(US11583532, Example 8.3)
Affinity DataIC50: 0.300nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593954BDBM593954(6-{[6-Bromo-5-(difluoromethoxy)pyridin-2-yl]methyl...)
Affinity DataIC50: 0.300nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593947BDBM593947(6-{[5-Bromo-6-(2,2-difluoropropoxy)pyridin-2-yl]me...)
Affinity DataIC50: 0.310nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593997BDBM593997(1-[6-({7-Amino-5-methyl-[1,2,4]triazolo[1,5-a]pyri...)
Affinity DataIC50: 0.310nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593952BDBM593952(US11583532, Example 3.3)
Affinity DataIC50: 0.320nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 594012BDBM594012(US11583532, Example 23.3)
Affinity DataIC50: 0.360nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593969BDBM593969(6-({7-amino-5-methyl-[1,2,4]triazolo[1,5-a]pyrimid...)
Affinity DataIC50: 0.370nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593949BDBM593949(6-{[6-(Furan-2-yl)-5-(trifluoromethyl)pyridin-2-yl...)
Affinity DataIC50: 0.400nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593986BDBM593986(US11583532, Example 9.3)
Affinity DataIC50: 0.560nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593970BDBM593970(US11583532, Example 7.2)
Affinity DataIC50: 0.570nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593950BDBM593950(US11583532, Example 2.2)
Affinity DataIC50: 0.590nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593951BDBM593951(5-Methyl-6-{[6-(morpholin-4-yl)-5-(trifluoromethyl...)
Affinity DataIC50: 0.650nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593993BDBM593993(US11583532, Example 11.2)
Affinity DataIC50: 0.680nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593989BDBM593989(6-{[5-Bromo-6-(4-fluoro-1H-pyrazol-1-yl)pyridin-2-...)
Affinity DataIC50: 0.680nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593965BDBM593965(US11583532, Example 6.2)
Affinity DataIC50: 0.690nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593974BDBM593974(US11583532, Example 7.6)
Affinity DataIC50: 0.690nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 594013BDBM594013(US11583532, Example 23.4)
Affinity DataIC50: 0.700nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593952BDBM593952(US11583532, Example 3.3)
Affinity DataIC50: 0.760nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 594014BDBM594014(US11583532, Example 23.5)
Affinity DataIC50: 0.830nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593998BDBM593998(Methyl 5-({7-amino-5-methyl-[1,2,4]triazolo[1,5-a]...)
Affinity DataIC50: 0.830nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 594018BDBM594018(5-Chloro-6-{[2-methoxy-4-(trifluoromethyl)phenyl]m...)
Affinity DataIC50: 0.830nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 594015BDBM594015(US11583532, Example 23.6)
Affinity DataIC50: 0.860nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593973BDBM593973(US11583532, Example 7.5)
Affinity DataIC50: 0.920nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593975BDBM593975(US11583532, Example 7.7)
Affinity DataIC50: 0.930nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593992BDBM593992({[5-({7-Amino-5-methyl-[1,2,4]triazolo[1,5-a]pyrim...)
Affinity DataIC50: 0.950nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 594003BDBM594003(5-(Difluoromethyl)-6-{[4-(trifluoromethyl)phenyl]m...)
Affinity DataIC50: 0.950nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 594019BDBM594019(US11583532, Example 25.2)
Affinity DataIC50: 1nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593976BDBM593976(US11583532, Example 7.8)
Affinity DataIC50: 1.10nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593957BDBM593957(US11583532, Example 4.4)
Affinity DataIC50: 1.10nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593956BDBM593956(US11583532, Example 4.3)
Affinity DataIC50: 1.10nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593977BDBM593977(US11583532, Example 7.9)
Affinity DataIC50: 1.30nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593972BDBM593972(US11583532, Example 7.4)
Affinity DataIC50: 1.30nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593995BDBM593995(5-Methyl-6-({6-[1-methyl-3-(trifluoromethyl)-1H-py...)
Affinity DataIC50: 1.70nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593968BDBM593968(US11583532, Example 6.5)
Affinity DataIC50: 1.70nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593967BDBM593967(US11583532, Example 6.4)
Affinity DataIC50: 1.90nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593955BDBM593955(US11583532, Example 4.2)
Affinity DataIC50: 1.90nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593948BDBM593948(US11583532, Example 1.2)
Affinity DataIC50: 2nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593996BDBM593996(US11583532, Example 13.2)
Affinity DataIC50: 2.10nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593971BDBM593971(US11583532, Example 7.3)
Affinity DataIC50: 2.30nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593984BDBM593984(6-({7-Amino-5-methyl-[1,2,4]triazolo[1,5-a]pyrimid...)
Affinity DataIC50: 2.40nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593958BDBM593958(US11583532, Example 4.5)
Affinity DataIC50: 2.40nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593990BDBM593990(US11583532, Example 10.2)
Affinity DataIC50: 2.80nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593960BDBM593960(US11583532, Example 4.7)
Affinity DataIC50: 2.90nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 593959BDBM593959(US11583532, Example 4.6)
Affinity DataIC50: 3nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

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