Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with all data for entry = 11166
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Revolution Medicines

US Patent
LigandPNGBDBM596379(US11596633, Compound C)
Affinity DataIC50:  1.29nMAssay Description:Objective: To demonstrate the inhibition of SHP2 activity with Compounds A, B, and C. Without wishing to be bound by theory, SHP is allosterically ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Revolution Medicines

US Patent
LigandPNGBDBM50546219(CHEMBL4752026 | US11596633, Compound B | US1170239...)
Affinity DataIC50:  1.55nMAssay Description:Objective: To demonstrate the inhibition of SHP2 activity with Compounds A, B, and C. Without wishing to be bound by theory, SHP is allosterically ac...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Revolution Medicines

US Patent
LigandPNGBDBM596328(US11596633, Compound A)
Affinity DataIC50:  2.19nMAssay Description:Objective: To demonstrate the inhibition of SHP2 activity with Compounds A, B, and C. Without wishing to be bound by theory, SHP is allosterically ac...More data for this Ligand-Target Pair
In DepthDetails US Patent