Compile Data Set for Download or QSAR
Report error Found 170 Enz. Inhib. hit(s) with all data for entry = 11175
LigandChemical structure of BindingDB Monomer ID 597662BDBM597662(US11603374, Example 17)
Affinity DataIC50: 0.300nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597647BDBM597647(US11603374, Example 2)
Affinity DataIC50: 0.400nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597647BDBM597647(US11603374, Example 2)
Affinity DataIC50: 0.400nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597646BDBM597646(US11603374, Example 1)
Affinity DataIC50: 0.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597646BDBM597646(US11603374, Example 1)
Affinity DataIC50: 0.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597673BDBM597673(US11603374, Example 28)
Affinity DataIC50: 0.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597673BDBM597673(US11603374, Example 28)
Affinity DataIC50: 0.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597674BDBM597674(US11603374, Example 29)
Affinity DataIC50: 0.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597672BDBM597672((3-(4-amino-5-(5- cyclopropylisoxazol-3-yl)- 7H-py...)
Affinity DataIC50: 0.600nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597675BDBM597675(US11603374, Example 30)
Affinity DataIC50: 0.700nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597648BDBM597648(US11603374, Example 3)
Affinity DataIC50: 0.700nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597663BDBM597663(7-cyclobutyl-5-(5- cyclopropylisoxazol-3-yl)- 7H-p...)
Affinity DataIC50: 0.700nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597677BDBM597677(US11603374, Example 32)
Affinity DataIC50: 0.700nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597662BDBM597662(US11603374, Example 17)
Affinity DataIC50: 0.800nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597662BDBM597662(US11603374, Example 17)
Affinity DataIC50: 0.800nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597649BDBM597649(US11603374, Example 4)
Affinity DataIC50: 0.800nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597669BDBM597669(5-(5-cyclopropylisoxazol-3- yl)-7-(1,1,1-trifluoro...)
Affinity DataIC50: 0.800nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597648BDBM597648(US11603374, Example 3)
Affinity DataIC50: 0.800nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597672BDBM597672((3-(4-amino-5-(5- cyclopropylisoxazol-3-yl)- 7H-py...)
Affinity DataIC50: 0.900nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597663BDBM597663(7-cyclobutyl-5-(5- cyclopropylisoxazol-3-yl)- 7H-p...)
Affinity DataIC50: 0.900nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597673BDBM597673(US11603374, Example 28)
Affinity DataIC50: 0.900nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597668BDBM597668(2-(4-amino-5-(5- cyclopropylisoxazol-3-yl)- 7H-pyr...)
Affinity DataIC50: 1nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597672BDBM597672((3-(4-amino-5-(5- cyclopropylisoxazol-3-yl)- 7H-py...)
Affinity DataIC50: 1nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597675BDBM597675(US11603374, Example 30)
Affinity DataIC50: 1.10nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597674BDBM597674(US11603374, Example 29)
Affinity DataIC50: 1.10nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597648BDBM597648(US11603374, Example 3)
Affinity DataIC50: 1.20nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597665BDBM597665(US11603374, Example 20)
Affinity DataIC50: 1.30nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597669BDBM597669(5-(5-cyclopropylisoxazol-3- yl)-7-(1,1,1-trifluoro...)
Affinity DataIC50: 1.30nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597649BDBM597649(US11603374, Example 4)
Affinity DataIC50: 1.40nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597646BDBM597646(US11603374, Example 1)
Affinity DataIC50: 1.40nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597647BDBM597647(US11603374, Example 2)
Affinity DataIC50: 1.40nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597663BDBM597663(7-cyclobutyl-5-(5- cyclopropylisoxazol-3-yl)- 7H-p...)
Affinity DataIC50: 1.40nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597676BDBM597676(US11603374, Example 31)
Affinity DataIC50: 1.40nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597676BDBM597676(US11603374, Example 31)
Affinity DataIC50: 1.40nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597662BDBM597662(US11603374, Example 17)
Affinity DataIC50: 1.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597674BDBM597674(US11603374, Example 29)
Affinity DataIC50: 1.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597678BDBM597678(US11603374, Example 33)
Affinity DataIC50: 1.60nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597647BDBM597647(US11603374, Example 2)
Affinity DataIC50: 1.80nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597668BDBM597668(2-(4-amino-5-(5- cyclopropylisoxazol-3-yl)- 7H-pyr...)
Affinity DataIC50: 1.90nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597677BDBM597677(US11603374, Example 32)
Affinity DataIC50: 1.90nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597672BDBM597672((3-(4-amino-5-(5- cyclopropylisoxazol-3-yl)- 7H-py...)
Affinity DataIC50: 2nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597674BDBM597674(US11603374, Example 29)
Affinity DataIC50: 2.10nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597646BDBM597646(US11603374, Example 1)
Affinity DataIC50: 2.10nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597649BDBM597649(US11603374, Example 4)
Affinity DataIC50: 2.30nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597671BDBM597671(5-(5-cyclopropylisoxazol-3- yl)-7-(oxetan-3-yl)-7H...)
Affinity DataIC50: 2.30nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597671BDBM597671(5-(5-cyclopropylisoxazol-3- yl)-7-(oxetan-3-yl)-7H...)
Affinity DataIC50: 2.30nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 597665BDBM597665(US11603374, Example 20)
Affinity DataIC50: 2.40nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597649BDBM597649(US11603374, Example 4)
Affinity DataIC50: 2.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597646BDBM597646(US11603374, Example 1)
Affinity DataIC50: 2.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597669BDBM597669(5-(5-cyclopropylisoxazol-3- yl)-7-(1,1,1-trifluoro...)
Affinity DataIC50: 2.5nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

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