Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 11183
LigandChemical structure of BindingDB Monomer ID 597838BDBM597838(US11608337, Example 18 | 2-(2-methylbiphenyl-3-yl)...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597844BDBM597844(US11608337, Example 24 | 5-methyl-2-(2-methylbiphe...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597843BDBM597843(US11608337, Example 23 | 2-(2-methylbiphenyl-3-yl)...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597842BDBM597842(US11608337, Example 22 | 2-(2-methylbiphenyl-3-yl)...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597848BDBM597848(US11608337, Example 28 | 2-(3′-methoxy-2-met...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597854BDBM597854(US11608337, Example 33 | 2-(3′-ethoxy-2-meth...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597853BDBM597853(US11608337, Example 32 | 2-(3-cyclohex-1-en-1-yl-2...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597824BDBM597824(US11608337, Example 5 | (2S)-1-[2-(2-methylbipheny...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597858BDBM597858(US11608337, Example 37 | 2-(2′,6′-difl...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597804BDBM597804(US11608337, Example 4 | 2-[2-(2-methylbiphenyl-3-y...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597801BDBM597801(US11608337, Example 3 | 5-methyl-2-(2-methylbiphen...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50540067BDBM50540067(CHEMBL4636289 | US11608337, Example 2)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597855BDBM597855(US11608337, Example 34 | 2-(3′,5′-dime...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597827BDBM597827(US11608337, Example 8 | 4-[2-(2-methylbiphenyl-3-y...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597861BDBM597861(US11608337, Example 40 | 2-[2-methyl-3-(1-methyl-1...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597826BDBM597826(US11608337, Example 7 | 4-[2-(2-methylbiphenyl-3-y...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597860BDBM597860(US11608337, Example 39 | 2-[2′-methyl-3̸...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597859BDBM597859(US11608337, Example 38 | 2′-methyl-3′-...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597832BDBM597832(US11608337, Example 13 | 2-(2,3-dihydro-1,4-benzod...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597835BDBM597835(US11608337, Example 16 | 2-[4-(2,3-dihydro-1,4-ben...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597834BDBM597834(US11608337, Example 15 | 2-[4-(3-methoxyphenyl)-3-...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597833BDBM597833(US11608337, Example 14 | 2-(3-methyl-4-phenylpyrid...)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597857BDBM597857(US11608337, Example 36 | 2-{[2′-methyl-3R...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597856BDBM597856(US11608337, Example 35 | 4-(2,3-dihydro-1,4-benzod...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597845BDBM597845(US11608337, Example 25 | 2-(2-methylbiphenyl-3-yl)...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597828BDBM597828(US11608337, Example 9 | Trans-2-{[2-(2-methylbiphe...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597825BDBM597825(US11608337, Example 6 | 2-(2-methylbiphenyl-3-yl)-...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597831BDBM597831(US11608337, Example 12 | 2-(2-methylbiphenyl-3-yl)...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597847BDBM597847(US11608337, Example 27 | 2-[2-methyl-3-(3-thienyl)...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597830BDBM597830(US11608337, Example 11 | {4-[2-(2-methylbiphenyl-3...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597829BDBM597829(US11608337, Example 10 | 2-(2-methylbiphenyl-3-yl)...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597836BDBM597836(US11608337, Example 17 | 2-(2-methylbiphenyl-3-yl)...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597850BDBM597850(US11608337, Example 30 | 2-[3-(2-methoxypyridin-4-...)
Affinity DataIC50: 300nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597841BDBM597841(US11608337, Example 21 | 2-(2-methylbiphenyl-3-yl)...)
Affinity DataIC50: 5.25E+3nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597840BDBM597840(US11608337, Example 20 | 2-(2-methylbiphenyl-3-yl)...)
Affinity DataIC50: 5.25E+3nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597839BDBM597839(US11608337, Example 19 | 7,7-dimethyl-2-(2-methylb...)
Affinity DataIC50: 5.25E+3nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597849BDBM597849(US11608337, Example 29 | 2-[3-(3,6-dihydro-2H-pyra...)
Affinity DataIC50: 5.25E+3nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597846BDBM597846(US11608337, Example 26 | 2-[2-(2,3-dihydro-1,4-ben...)
Affinity DataIC50: 5.25E+3nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597787BDBM597787(US11608337, Example 1 | 2-(2-methylbiphenyl-3-yl)-...)
Affinity DataIC50: 5.25E+3nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 597852BDBM597852(US11608337, Example 31 | 2-[3-(5-fluoropyridin-2-y...)
Affinity DataIC50: 5.25E+3nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent