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Found 24 Enz. Inhib. hit(s) with all data for entry = 11189
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM597988(US11612603, Compound 1)
Affinity DataIC50: <100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598003((E)-3-(1H-1,2,3-triazol-5-yl)methyl)-6-(6-chloro-2...)
Affinity DataIC50: <100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598023((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: <100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598022((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: <100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598016((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: <100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598015((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50: <100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598009(US11612603, Compound 16)
Affinity DataIC50: <100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598008((E)-3-(1H-1,2,3-triazol-5-yl)methyl)-6-(6-chloro-2...)
Affinity DataIC50: <100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM597995((E)-3-(1H-1,2,3-triazol-5-yl)methyl)-6-(6-chloro-2...)
Affinity DataIC50: <100nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598020((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50:  350nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM597997((E)-3-(1H-1,2,3-triazol-5-yl)methyl)-6-(6-chloro-2...)
Affinity DataIC50:  350nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598024((E)-6-(6-chloro-2-methyl-2H-indazol-5-yl)imino)-3-...)
Affinity DataIC50:  350nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM597999((E)-3-((1H-1,2,3-triazol-5-yl)methyl)-1-(4-bromoph...)
Affinity DataIC50:  350nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM597992((E)-3-(1H-1,2,3-triazol-5-yl)methyl)-6-(6-chloro-2...)
Affinity DataIC50:  350nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598021(US11612603, Compound 21)
Affinity DataIC50:  350nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598019((E)-6-(2-methyl-2H-indazol-5-yl)imino)-3-(1-ethyl-...)
Affinity DataIC50:  350nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM597998((E)-3-(1H-1,2,3-triazol-5-yl)methyl)-6-(6-chloro-2...)
Affinity DataIC50:  350nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598007((E)-3-(1H-1,2,3-triazol-5-yl)methyl)-6-(6-chloro-2...)
Affinity DataIC50:  750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598006((E)-3-(1H-1,2,3-triazol-5-yl)methyl)-6-(6-chloro-2...)
Affinity DataIC50:  750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM597990((E)-3-(1H-1,2,3-triazol-5-yl)methyl)-6-(6-chloro-2...)
Affinity DataIC50:  750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM597989((E)-3-((1H-1,2,3-triazol-5-yl)methyl)-1-benzyl-6-(...)
Affinity DataIC50:  750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM597991((E)-3-(1H-1,2,3-triazol-5-yl)methyl)-1-(4-(tert-bu...)
Affinity DataIC50:  750nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM598002((E)-3-((1H-1,2,3-triazol-5-yl)methyl)-1-([1,1-biph...)
Affinity DataIC50: >1.00E+3nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Shaanxi Panlong Pharmaceutical

US Patent
LigandPNGBDBM597993((E)-3-(1H-1,2,3-triazol-5-yl)methyl)-6-(6-chloro-2...)
Affinity DataIC50: >1.00E+3nMAssay Description:The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer. 10 μL of the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent