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Found
15
Enz. Inhib. hit(s) with all data for entry = 11204
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600503
(methyl 6-(2,4-dioxo-1,3,7- triazaspiro[4.4]nonan-7...)
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Affinity Data
Kd: 2nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
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Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600500
(7-((S)-1,2,3,4- tetrahydronaphthalene-1-carbonyl)-...)
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Affinity Data
Kd: 3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600499
(7-benzoyl-1,3,7- triazaspiro[4.4]nonane-2,4-dione ...)
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Affinity Data
Kd: 4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600510
(7-(pyrazolo[1,5-a]pyridine-3- carbonyl)-2,7- diaza...)
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Affinity Data
Kd: 6nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600506
(7-(thiazolo[4,5-b]pyridin-2-yl)- 1,3,7-triazaspiro...)
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Affinity Data
Kd: 7nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600504
(N-(3-(2,4-dioxo-1,3,7- triazaspiro[4.4]nonane-7- c...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 10nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600508
(methyl 6-(6,8-dioxo-2,7- diazaspiro[4.4]nonan-2-yl...)
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Affinity Data
Kd: 10nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600511
(7-benzoyl-2,7- diazaspiro[4.4]nonane-1,3-dione | U...)
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Affinity Data
Kd: 15nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600509
(7-(benzo[d]thiazol-2-yl)-2,7- diazaspiro[4.4]nonan...)
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Affinity Data
Kd: 18nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600513
((S)-7-(benzo[d]thiazole-5-carbonyl)- 1,3,7-triazas...)
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Affinity Data
Kd: 23nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600512
((R)-7-(benzo[d]thiazole-5- carbonyl)-1,3,7- triaza...)
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Affinity Data
Kd: 26nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600501
(7-(benzo[d]thiazol-2-yl)-1,3,7- triazaspiro[4.4]no...)
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Affinity Data
Kd: 31nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600507
(7-(benzo[d]thiazole-5-carbonyl)- 1,3,7-triazaspiro...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 32nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600502
(7-(pyrazolo[1,5-a]pyridine-3- carbonyl)-1,3,7- tri...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 37nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
DNA damage-binding protein 1/Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM600505
(N-(4-(2,4-dioxo-1,3,7- triazaspiro[4.4]nonane-7- c...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 161nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
5/22/2023
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL