Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 11240
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601779(Exenatide | Exendin-4 | US11643403, Control substa...)
Affinity DataIC50: 4.30E+3nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601926(2-((4-(3-((4-cyano-2- fluorobenzyl)oxy)phenyl) pip...)
Affinity DataIC50: 1.85E+4nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601907((S)-2-((4-(3-((4-cyano-2- fluorobenzyl)oxy)phenyl)...)
Affinity DataIC50: 3.46E+4nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601922(2-(((S)-4-(6-((4-cyano-2- fluorobenzyl)oxy)pyrazin...)
Affinity DataIC50: 5.58E+4nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601906((S)-2-((4-(6-((5-cyanopyridin-2- yl)methoxy)pyridi...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601780(2-(((S)-4-(6-((5-cyanopyridin-2- yl)methoxy)pyridi...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601923(2-(((S)-4-(6-((5-cyanopyridin-2-yl)methoxy)pyridin...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601932((S)-2-((4-(6-(5-chloropyridin-2-yl)methoxy)pyridin...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601931((S)-2-((4-(6-((5-chloro-3-fluoropyridin-2-yl)metho...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601930((S)-2-((4-(3-(5-cyanopyridin-2-yl)methoxy)phenyl)p...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ildong Pharmaceutical

US Patent
LigandPNGBDBM601929((S)-2-((4-(3-(5-cyanopyridin-2-yl)methoxy)phenyl)p...)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibition of activity of hERG (human ether-a-go-go related gene) potassium channel by the compounds was evaluated by using an automatic whole-ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
US Patent