Compile Data Set for Download or QSAR
Report error Found 327 Enz. Inhib. hit(s) with all data for entry = 11246
TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602345(US11648254, Compound 241 | tert-butyl (R)-3-((1,1-...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602343(US11648254, Compound 239 | (R)-4-(4-((1-(3-(1,1-di...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602342(US11648254, Compound 238 | (R)-4-(4-((1-(3-(1,1-di...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602349(US11648254, Compound 245 | (R)-1-(4-((1-(3-(1,1-di...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602348(US11648254, Compound 244 | (R)-1-(4-((1-(3-(1,1-di...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602347(US11648254, Compound 243 | (R)-N-(1-(3-(2-(azetidi...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602346(US11648254, Compound 242 | (R)-N-(1-(3-(1,1-difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602355(US11648254, Compound 249 | (R)-4-(2-methyl-4-((1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602354(US11648254, Compound 248 | (R)-4-(4-((1-(2-fluoro-...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602353(US11648254, Compound 247 | (R)-4-(4-((1-(2-fluoro-...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602350(US11648254, Compound 246 | (R)-N-(1-(3-(difluorome...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602359(US11648254, Compound 253 | (R)-7-(azetidin-3-yloxy...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602358(US11648254, Compound 252 | (R)-N-(1-(3-(difluorome...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602357(US11648254, Compound 251 | (R)-4-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602356(US11648254, Compound 250 | (R)-4-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602328(US11648254, Compound 224 | (R)-7-chloro-N-(1-(3-(d...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602327(US11648254, Compound 223 | (R)-7-chloro-N-(1-(3-(d...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602326(US11648254, Compound 222 | (R)-7-chloro-N-(1-(3-(d...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602333(US11648254, Compound 229 | (R)-4-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602331(US11648254, Compound 227 | (R)-4-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602330(US11648254, Compound 226 | 1-(4-(((R)-1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602337(US11648254, Compound 233 | 1-(4-(((R)-1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602336(US11648254, Compound 232 | (R)-1-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602335(US11648254, Compound 231 | (R)-4-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602340(US11648254, Compound 236 | (R)-6-(1-isopropylpiper...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602339(US11648254, Compound 235 | 1-(4-(((R)-1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602338(US11648254, Compound 234 | (R)-1-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602381(US11648254, Compound 273 | (R)-1,1-difluoro-1-(2-f...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602380(US11648254, Compound 272 | (R)-4-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602379(US11648254, Compound 271 | (R)-4-(4-((1-(3-(2-(2- ...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602378(US11648254, Compound 270 | 1-(4-(((R)-1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602385(US11648254, Compound 277 | (R)-1-(4-((1-(3-(2-(aze...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602384(US11648254, Compound 276 | (R)-1-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602386(US11648254, Compound 278 | (R)-1-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602393(US11648254, Compound 285 | (R)-1-isopropyl-4-(7-me...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602392(US11648254, Compound 284 | (R)-1-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602391(US11648254, Compound 283 | (R)-4-(4-((1-(3-(difluo...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602364(US11648254, Compound 257 | (R)-4-(7-chloro-4-((1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602363(US11648254, Compound 256 | 1-(4-(((R)-1-(3-((S)-1,...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602361(US11648254, Compound 255 | (R)-N-(1-(3-(difluorome...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602360(US11648254, Compound 254 | (R)-N-(1-(3-(difluorome...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602369(US11648254, Compound 261 | (R)-4-(7-chloro-4-((1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602367(US11648254, Compound 260 | (R)-4-(7-chloro-4-((1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602366(US11648254, Compound 259 | (R)-4-(7-chloro-4-((1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602365(US11648254, Compound 258 | 1-(7-chloro-4-(((R)-1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602373(US11648254, Compound 265 | 1-(7-chloro-4-(((R)-1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602372(US11648254, Compound 264 | 1-(4-(((R)-1-(3-((R)-1,...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602371(US11648254, Compound 263 | (R)-N-(1-(3-(difluoro(1...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602370(US11648254, Compound 262 | (R)-4-(7-chloro-4-((1-(...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

TargetSon of sevenless homolog 1(Human)
Kumquat Biosciences

US Patent
LigandPNGBDBM602377(US11648254, Compound 269 | (R)-7-chloro-N-(1-(3-(d...)
Affinity DataIC50: 100nMAssay Description:The ability of any compound of the present disclosure to reduce a Ras protein signaling output by, e.g., interfering or disrupting interaction (or bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent

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