Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 11277
TargetMultidrug and toxin extrusion protein 2(Human)
Gilead Sciences

US Patent
LigandPNGBDBM273241(2-(4-(2-(7,8-dimethyl-[1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50: 300nMAssay Description:MATE2-K (multidrug and toxin extrusion protein 2) is expressed in the apical membrane in the kidney and mediates the elimination of compounds to urin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent

TargetMultidrug and toxin extrusion protein 2(Human)
Gilead Sciences

US Patent
LigandPNGBDBM604822(US11661431, Example B-1)
Affinity DataIC50: 1.10E+3nMAssay Description:MATE2-K (multidrug and toxin extrusion protein 2) is expressed in the apical membrane in the kidney and mediates the elimination of compounds to urin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent

TargetMultidrug and toxin extrusion protein 2(Human)
Gilead Sciences

US Patent
LigandPNGBDBM604824(US11661431, Example 67)
Affinity DataIC50: 6.20E+3nMAssay Description:MATE2-K (multidrug and toxin extrusion protein 2) is expressed in the apical membrane in the kidney and mediates the elimination of compounds to urin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent

TargetMultidrug and toxin extrusion protein 2(Human)
Gilead Sciences

US Patent
LigandPNGBDBM604823(US11661431, Example 56)
Affinity DataIC50: 7.70E+3nMAssay Description:MATE2-K (multidrug and toxin extrusion protein 2) is expressed in the apical membrane in the kidney and mediates the elimination of compounds to urin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent

TargetMultidrug and toxin extrusion protein 2(Human)
Gilead Sciences

US Patent
LigandPNGBDBM604837(US11661431, Example 91)
Affinity DataIC50: 7.80E+3nMAssay Description:MATE2-K (multidrug and toxin extrusion protein 2) is expressed in the apical membrane in the kidney and mediates the elimination of compounds to urin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent

TargetMultidrug and toxin extrusion protein 2(Human)
Gilead Sciences

US Patent
LigandPNGBDBM604825(US11661431, Example 79)
Affinity DataIC50: 8.10E+3nMAssay Description:MATE2-K (multidrug and toxin extrusion protein 2) is expressed in the apical membrane in the kidney and mediates the elimination of compounds to urin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent

TargetMultidrug and toxin extrusion protein 2(Human)
Gilead Sciences

US Patent
LigandPNGBDBM604838(101 | US11661431, Example 100)
Affinity DataIC50: 9.70E+3nMAssay Description:MATE2-K (multidrug and toxin extrusion protein 2) is expressed in the apical membrane in the kidney and mediates the elimination of compounds to urin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent

TargetMultidrug and toxin extrusion protein 2(Human)
Gilead Sciences

US Patent
LigandPNGBDBM604833(US11661431, Example 82)
Affinity DataIC50: 1.45E+4nMAssay Description:MATE2-K (multidrug and toxin extrusion protein 2) is expressed in the apical membrane in the kidney and mediates the elimination of compounds to urin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2023
Entry Details
US Patent