Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 11410
TargetSerine/threonine-protein kinase SIK2(Human)
The General Hospital

US Patent
LigandPNGBDBM192714(YKL-05-095 (3) | US11725011, Compound YKL-05-95)
Affinity DataIC50: 6nMAssay Description:IC50's for selected compounds in Table 5 below were measured by Caliper-based mobility shift assay (PerkinElmer). For these experiments, full len...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
The General Hospital

US Patent
LigandPNGBDBM192715(YKL-05-096 (4) | US11725011, Compound YKL-05-96)
Affinity DataIC50: 34nMAssay Description:IC50's for selected compounds in Table 5 below were measured by Caliper-based mobility shift assay (PerkinElmer). For these experiments, full len...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK2(Human)
The General Hospital

US Patent
LigandPNGBDBM192716(YKL-05-099 (5) | US11725011, Compound YKL-05-99)
Affinity DataIC50: 40nMAssay Description:IC50's for selected compounds in Table 5 below were measured by Caliper-based mobility shift assay (PerkinElmer). For these experiments, full len...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2023
Entry Details
US Patent