Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 11418
TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50606735BDBM50606735(CHEMBL5219718 | US11731973, Example 3)
Affinity DataKi:  0.300nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50606737BDBM50606737(CHEMBL5218727 | US11731973, Example 5)
Affinity DataKi:  0.400nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50606738BDBM50606738(CHEMBL5218590 | US11731973, Example 6)
Affinity DataKi:  0.5nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50606740BDBM50606740(CHEMBL5220536 | US11731973, Example 30)
Affinity DataKi:  0.580nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50606742BDBM50606742(CHEMBL5220948 | US11731973, Example 9)
Affinity DataKi:  0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613740BDBM613740(3-(2-aminobenzoxazol-5-yl)-1-(2,2- dimethylbutyl)-...)
Affinity DataKi:  0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50606739BDBM50606739(CHEMBL5220152 | US11731973, Example 7)
Affinity DataKi:  0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50606741BDBM50606741(CHEMBL5219710 | US11731973, Example 1)
Affinity DataKi:  0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50606736BDBM50606736(CHEMBL5218916 | US11731973, Example 10)
Affinity DataKi:  0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613743BDBM613743(1-(2,2-dimethylpropyl)-3-(2- ethylaminobenzoxazol-...)
Affinity DataKi:  0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613734BDBM613734(3-(2-amino-6-fluorobenzoxazol-5-yl)- 1-((S)-1,3-di...)
Affinity DataKi:  1nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613746BDBM613746(3-(2-aminobenzoxazol-5-yl)-1-(2,2- dimethylbut-3-y...)
Affinity DataKi:  1.20nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613745BDBM613745((+)-3-(2-aminobenzoxazol-5-yl)-1- ((S)-2-methyl-2-...)
Affinity DataKi:  1.20nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613744BDBM613744(3-(2-aminobenzoxazol-5-yl)-1-(2,2- dimethylbut-3-e...)
Affinity DataKi:  1.20nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613736BDBM613736(3-(2-amino-6-fluorobenzoxazol-5-yl)- 1-(1-methylcy...)
Affinity DataKi:  1.40nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613748BDBM613748(3-[4,6-diamino-3-(2- aminobenzoxazol-5-yl)pyrazolo...)
Affinity DataKi:  1.5nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613749BDBM613749(3-(2-aminobenzoxazol-5-yl)-1-(2- methyl-2-methylsu...)
Affinity DataKi:  1.70nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613750BDBM613750(3-(2-amino-4-chlorobenzoxazol-5-yl)- 1-(2,2-dimeth...)
Affinity DataKi:  1.80nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613751BDBM613751(3-(2-amino-6-methoxybenzoxazol-5- yl)-1-(2,2-dimet...)
Affinity DataKi:  2.10nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613752BDBM613752(2-[4,6-diamino-1-(2,2- dimethylpropyl)-1H-pyrazolo...)
Affinity DataKi:  2.30nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613753BDBM613753(3-(2-amino-6-methoxybenzoxazol-5- yl)-1-(2,2-dimet...)
Affinity DataKi:  2.90nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50529395BDBM50529395(CHEMBL4529672 | US11731973, Example 21)
Affinity DataKi:  3.80nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613755BDBM613755(3-(2-aminobenzoxazol-5-yl)-1-(2- ethyl-2-methanesu...)
Affinity DataKi:  3.90nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613756BDBM613756(3-(2-aminobenzoxazol-5-yl)-4-chloro- 1-isobutyl-1H...)
Affinity DataKi:  5.80nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50529393BDBM50529393(CHEMBL4564479 | US11731973, Example 24)
Affinity DataKi:  6.10nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613758BDBM613758(3-(2-amino-6-chlorobenzoxazol-5-yl)- 1-((S)-1,2-di...)
Affinity DataKi:  8.10nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 50529398BDBM50529398(CHEMBL4549761 | US11731973, Example 31)
Affinity DataKi:  10nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613759BDBM613759(3-(2-aminobenzoxazol-5-yl)-1- isopropyl-N*6*-methy...)
Affinity DataKi:  13.4nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613760BDBM613760(5-(6-amino-4-methyl-1-neopentyl- 1H-pyrazolo[3,4-d...)
Affinity DataKi:  14.3nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613761BDBM613761(3-(2-cyclopropylaminobenzoxazol-5- yl)-1-isopropyl...)
Affinity DataKi:  21nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 613762BDBM613762(3-(2-amino-7-methylbenzoxazol-5- yl)-1-(2,2-dimeth...)
Affinity DataKi:  102nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent