Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 11487
TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620408(US11767305, Compound S-5-MAPB | US20250019357, Com...)
Affinity DataIC50: 60.4nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620423(US11767305, Compound S-6-MAPB | US20250019357, Com...)
Affinity DataIC50: 90.9nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620425(US11767305, Compound S-5-MBPB | US20250019357, Com...)
Affinity DataIC50: 124nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620422(US11767305, Compound R-5-MAPB | US20250019357, Com...)
Affinity DataIC50: 150nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620426(US11767305, Compound R-5-MBPB | US20250019357, Com...)
Affinity DataIC50: 212nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620427(US11767305, Compound S-6-MBPB)
Affinity DataIC50: 217nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620431(US11767305, Compound (-)-BK-6-MAPB | US20250019357...)
Affinity DataIC50: 275nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620429(US11767305, Compound (-)-BK-5-MAPB | US20250019357...)
Affinity DataIC50: 284nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM50010588(DL-(3,4-Methylenedioxy)methamphetamine | N-Methyl-...)
Affinity DataIC50: 384nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620424(US11767305, Compound R-6-MAPB | US20250019357, Com...)
Affinity DataIC50: 623nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620428(US11767305, Compound R-6-MBPB)
Affinity DataIC50: 702nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620430(US11767305, Compound (+)-BK-5-MAPB | US20250019357...)
Affinity DataIC50: 2.09E+3nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
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TargetSodium-dependent serotonin transporter(Human)
Tactogen

US Patent
LigandPNGBDBM620432(US11767305, Compound (+)-BK-6-MAPB | US20250019357...)
Affinity DataIC50: 5.47E+3nMAssay Description:For the SERT uptake inhibition assay, 5 nM [3H]5-HT was used. To optimize uptake for a single transporter, unlabeled blockers were included to preven...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2023
Entry Details
Go to US Patent