Compile Data Set for Download or QSAR
Report error Found 482 Enz. Inhib. hit(s) with all data for entry = 11594
TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630876BDBM630876((7-((3,6-Dimethyl-5-(trifluoromethyl)pyridin-2-yl)...)
Affinity DataIC50: 0.100nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630668BDBM630668(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-(2-methyl...)
Affinity DataIC50: 0.200nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630869BDBM630869((7-((6-Ethoxy-5-(trifluoromethyl)pyridin-2-yl)oxy)...)
Affinity DataIC50: 0.220nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630706BDBM630706(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-((1-methy...)
Affinity DataIC50: 0.290nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630622BDBM630622(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(3-methyl...)
Affinity DataIC50: 0.300nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630649BDBM630649(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-(3-methyl...)
Affinity DataIC50: 0.400nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630685BDBM630685((6-(4-(Difluoromethyl)-2-methoxybenzyl)-2-azaspiro...)
Affinity DataIC50: 0.440nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630476BDBM630476((rac)-((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(3-...)
Affinity DataIC50: 0.5nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630868BDBM630868(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-((6-metho...)
Affinity DataIC50: 0.550nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630612BDBM630612((6-(4-Cyclopropyl-3-methylbenzyl)-2-azaspiro[3.3]h...)
Affinity DataIC50: 0.600nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630856BDBM630856(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-((3-methy...)
Affinity DataIC50: 0.760nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630620BDBM630620(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(2-isopro...)
Affinity DataIC50: 0.800nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630754BDBM630754((7-(3,5-Dimethylphenyl)-7-methoxy-2-azaspiro[3.5]n...)
Affinity DataIC50: 0.840nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630692BDBM630692(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-((6-isopr...)
Affinity DataIC50: 1nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630686BDBM630686(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(3-methox...)
Affinity DataIC50: 1nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630630BDBM630630(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(4-(trifl...)
Affinity DataIC50: 1.10nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630676BDBM630676(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-(3-isopro...)
Affinity DataIC50: 1.20nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630629BDBM630629((6-(4-Cyclopropylbenzyl)-2-azaspiro[3.3]heptan-2-y...)
Affinity DataIC50: 1.20nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630691BDBM630691(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-((6-metho...)
Affinity DataIC50: 1.20nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630883BDBM630883((7-((1,5-Dimethyl-1H-pyrrolo[2,3-b]pyridin-6-yl)ox...)
Affinity DataIC50: 1.20nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630865BDBM630865((7-((5-Cyclopropyl-6-methoxypyridin-2-yl)oxy)-2-az...)
Affinity DataIC50: 1.30nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630822BDBM630822((7-(4-Chloro-2-methylphenoxy)-2-azaspiro[3.5]nonan...)
Affinity DataIC50: 1.40nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630886BDBM630886(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-((1-methy...)
Affinity DataIC50: 1.40nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630772BDBM630772(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-(3-isopro...)
Affinity DataIC50: 1.5nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630564BDBM630564((6-(3-Cyclopropyl-2-methylbenzyl)-2-azaspiro[3.3]h...)
Affinity DataIC50: 1.70nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630477BDBM630477((rac)-((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(3-...)
Affinity DataIC50: 1.70nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630559BDBM630559((7-(3-Chloro-5-(trifluoromethoxy)phenyl)-2-azaspir...)
Affinity DataIC50: 1.70nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630617BDBM630617((6-(2-Cyclopropyl-3-methylbenzyl)-2-azaspiro[3.3]h...)
Affinity DataIC50: 1.70nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630849BDBM630849((7-((6-(Difluoromethyl)-5-ethylpyridin-2-yl)oxy)-2...)
Affinity DataIC50: 1.80nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630771BDBM630771((7-(3-Ethoxy-2-methylphenyl)-2-azaspiro[3.5]nonan-...)
Affinity DataIC50: 1.80nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630826BDBM630826(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-(2-methyl...)
Affinity DataIC50: 1.90nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630881BDBM630881((7-((1,3-Dimethyl-1H-pyrrolo[2,3-b]pyridin-6-yl)ox...)
Affinity DataIC50: 2nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630545BDBM630545((7-(3-(tert-Butyl)phenyl)-2-azaspiro[3.5]nonan-2-y...)
Affinity DataIC50: 2.10nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630636BDBM630636(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(2-methyl...)
Affinity DataIC50: 2.10nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630864BDBM630864((7-((5-Ethyl-6-methoxypyridin-2-yl)oxy)-2-azaspiro...)
Affinity DataIC50: 2.20nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630619BDBM630619(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(3-methyl...)
Affinity DataIC50: 2.20nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630595BDBM630595(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(4-isopro...)
Affinity DataIC50: 2.30nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630485BDBM630485((rac)-(6-(4-Cyclopropyl-2-methylphenyl)-2-azaspiro...)
Affinity DataIC50: 2.40nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630783BDBM630783(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-(6-isopro...)
Affinity DataIC50: 2.40nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630858BDBM630858(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-((6-methy...)
Affinity DataIC50: 2.40nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630875BDBM630875((7-((4,6-Dimethyl-5-(trifluoromethyl)pyridin-2-yl)...)
Affinity DataIC50: 2.70nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630820BDBM630820((7-(2-Chloro-5-methylphenoxy)-2-azaspiro[3.5]nonan...)
Affinity DataIC50: 2.80nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630606BDBM630606(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(2-(trifl...)
Affinity DataIC50: 2.80nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630774BDBM630774((7-(3-Cyclopropoxy-2-methylphenyl)-2-azaspiro[3.5]...)
Affinity DataIC50: 2.90nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630860BDBM630860((7-((5-Ethyl-6-(trifluoromethyl)pyridin-2-yl)oxy)-...)
Affinity DataIC50: 2.90nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630565BDBM630565(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(6-(2-methyl...)
Affinity DataIC50: 3nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630669BDBM630669(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-(4-methyl...)
Affinity DataIC50: 3nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630889BDBM630889(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(2-(2-methyl...)
Affinity DataIC50: 3.10nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630672BDBM630672(((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(7-(4-(trifl...)
Affinity DataIC50: 3.20nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 630562BDBM630562((rac)-((1s,3s)-3-Hydroxy-3-methylcyclobutyl)(2-(4-...)
Affinity DataIC50: 3.30nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent

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