Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 11619
TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633586(N ((S)-1-cyano-2-(3-fluoro-4′-(pentafluoro-1...)
Affinity DataIC50: 0.300nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633583((S) N ((S)-1-cyano-2-(2-fluoro-4-(3-(methyl-d3)-2-...)
Affinity DataIC50: 0.5nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633575((S) N ((S)-1-cyano-2-(2-fluoro-4-(3-methyl-2-oxo-2...)
Affinity DataIC50: 1.60nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633585(US11807635, Compound 35)
Affinity DataIC50: 4nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633584((S) N ((S)-1-cyano-2-(4′-cyano-3-fluoro-3...)
Affinity DataIC50: 4.90nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633576((S) N ((S)-1-cyano-2-(2-fluoro-4-(1-oxo-1,2,3,4-te...)
Affinity DataIC50: 6.70nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633582((S) N ((S)-1-cyano-2-(4′-cyano-3′-cycl...)
Affinity DataIC50: 7.40nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633580((S) N ((S)-1-cyano-2-(3-fluoro-4′-((4-methyl...)
Affinity DataIC50: 12.9nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633578((S) N ((S)-1-cyano-2-(4-(5-cyano-4-methylthiazol-2...)
Affinity DataIC50: 21nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633581((S) N ((S)-1-cyano-2-(2-fluoro-4-(4-methylthiazol-...)
Affinity DataIC50: 33nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633579((S) N ((S)-2-(4-(benzo[d]thiazol-2-yl)-2-fluorophe...)
Affinity DataIC50: 71nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Haisco Pharmaceuticals

US Patent
LigandPNGBDBM633577((S) N ((S)-1-cyano-2-(4-(cyclopentylethynyl)-2-flu...)
Affinity DataIC50: 239nMAssay Description:Recombinant human DPP1 enzyme (R&D Systems, Cat. No. 1071-CY) at a final concentration of 100 μg/mL was mixed with recombinant human cathepsin L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2023
Entry Details
US Patent