Compile Data Set for Download or QSAR
Report error Found 107 Enz. Inhib. hit(s) with all data for entry = 11631
TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635450(1-(tert-Butyl)-5-fluoro-N-(3-(3-fluoro-2-methyl- 8...)
Affinity DataIC50: 1nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635418(1-(tert-Butyl)-N-(5-(8-(3,6-dihydro-2H-pyran-4- yl...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635419(1-(tert-Butyl)-N-(2,3-difluoro-4-methyl-5-(8- morp...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635420(1-Tert-butyl-5-fluoro-N-{2-fluoro-4-methyl-5-[8- (...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635421(1-(tert-Butyl)-5-fluoro-N-(2-fluoro-4-methyl-5- (7...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635414(1-Tert-butyl-4-fluoro-N-{4-methyl-3-[8- (morpholin...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635415(1-(tert-Butyl)-5-fluoro-N-(2-fluoro-4-methyl-5- (2...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635416(1-Tert-butyl-2-fluoro-N-{2-fluoro-4-methyl-5-[2- m...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635417(1-Tert-butyl-N-{4-chloro-2-fluoro-5-[8- (morpholin...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635426(1-(tert-Butyl)-5-fluoro-N-(2-fluoro-4-methyl-5- (8...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635427(2-Tert-butyl-N-{2-fluoro-4-methyl-5-[8- (morpholin...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635428(2-Tert-butyl-N-{2-fluoro-4-methyl-5-[8- (morpholin...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635429(2-Tert-butyl-N-{4-methyl-3-[8-(morpholin-4- yl)imi...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635395(US11814384, Example 103 | 1-Tert-butyl-5-fluoro-N-...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635423(1-{Bicyclo[1.1.1]pentan-1-yl}-N-{2-fluoro-4- methy...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635424(N-{2-fluoro-4-methyl-5-[8-(morpholin-4- yl)imidazo...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635425(N-(5-(8-(8-oxa-3-azabicyclo[3.2.1]octan-3- yl)imid...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635402(US11814384, Example 119 | 3-fluoro-N-(2-fluoro-4-m...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635402(US11814384, Example 119 | 3-fluoro-N-(2-fluoro-4-m...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635402(US11814384, Example 119 | 3-fluoro-N-(2-fluoro-4-m...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635405(US11814384, Example 122 | N-(2-fluoro-4-methyl-5-(...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635399(US11814384, Example 113 | US11814384, Example 114 ...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635399(US11814384, Example 113 | US11814384, Example 114 ...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635401(1-Tert-butyl-2-fluoro-N-{2-fluoro-4-methyl-5-[8- (...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635410(1-(tert-Butyl)-5-fluoro-N-(6-methyl-5-(8- morpholi...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635411(1-(tert-Butyl)-5-fluoro-N-(5-methyl-4-(8- morpholi...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635412(1-(Tert-butyl)-N-(2-fluoro-4-methyl-5-(2-methyl- 8...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635413(1-Tert-butyl-4-fluoro-N-{2-fluoro-4-methyl-5-[8- (...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635405(US11814384, Example 122 | N-(2-fluoro-4-methyl-5-(...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635407(1-(1,1-Difluoro-2-methylpropan-2-yl)-N-{2- fluoro-...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635408(1-(1,2-Difluoro-2-methylpropyl)-N-(2-fluoro-4- met...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635409(N-{2-fluoro-4-methyl-5-[8-(morpholin-4- yl)imidazo...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635448(1-(tert-Butyl)-5-fluoro-N-(2-fluoro-5-(3-fluoro-2-...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635449(1-(tert-Butyl)-5-fluoro-N-(3-(3-fluoro-2-methyl- 8...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635444(N-(1-(tert-butyl)-5-fluoro-1H-pyrazol-4-yl)-2- flu...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635445(N-{2-Fluoro-4-methyl-5-[8-(morpholin-4- yl)imidazo...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635446(1-(tert-Butyl)-5-fluoro-N-(2-fluoro-4-methyl-5- (2...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635447(N-(1-(tert-butyl)-5-fluoro-1H-pyrazol-4-yl)-2- flu...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635456(2-(Tert-butyl)-N-(2-fluoro-4-methyl-5-(2-methyl- 8...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635458(2-Tert-butyl-N-{2-fluoro-4-methyl-5-[2-methyl- 8-(...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635459(2-Tert-butyl-N-{5-[2-cyclopropyl-5-(morpholin- 4-y...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635452(N-(1-(tert-butyl)-5-fluoro-1H-pyrazol-4-yl)-2- flu...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635453(N-(1-(tert-Butyl)-5-fluoro-1H-pyrazol-4-yl)-2- flu...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635432(1-(tert-Butyl)-5-fluoro-N-(2-fluoro-4-methyl-5- (5...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635433(N-(1-tert-butylpyrazol-4-yl)-2-fluoro-4-methyl-5- ...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635435(N-{2-Fluoro-4-methyl-5-[8-(morpholin-4- yl)imidazo...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635430(2-Tert-butyl-N-{2-fluoro-4-methyl-5-[8- (morpholin...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635431(2-{Bicyclo[1.1.1]pentan-1-yl}-N-{2-fluoro-4- methy...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635430(2-Tert-butyl-N-{2-fluoro-4-methyl-5-[8- (morpholin...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Kinnate Biopharma

US Patent
LigandPNGBDBM635431(2-{Bicyclo[1.1.1]pentan-1-yl}-N-{2-fluoro-4- methy...)
Affinity DataIC50: 5.5nMAssay Description:Small molecule inhibition of the BRAF kinases was measured using ADP-Glo assay. In the assay, ADP is converted to ATP in the presence of test kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2024
Entry Details
US Patent

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