Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 11694
TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
University of California

US Patent
LigandPNGBDBM640385(US11840523, LBC-00004 08)
Affinity DataIC50: 5.10nMAssay Description:Inhibitors (initial concentration of 10 or 60 μM, three-fold serial dilutions) were incubated with IRE1α* in cleavage buffer (20 mM HEPES, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
University of California

US Patent
LigandPNGBDBM640388(US11840523, LBC-00004 05 | US11840523, Compound 37)
Affinity DataIC50: 5.10nMAssay Description:Inhibitors (initial concentration of 10 or 60 μM, three-fold serial dilutions) were incubated with IRE1α* in cleavage buffer (20 mM HEPES, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
University of California

US Patent
LigandPNGBDBM640387(US11840523, LBC-00004 06)
Affinity DataIC50: 7.40nMAssay Description:Inhibitors (initial concentration of 10 or 60 μM, three-fold serial dilutions) were incubated with IRE1α* in cleavage buffer (20 mM HEPES, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent

TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Human)
University of California

US Patent
LigandPNGBDBM640386(US11840523, LBC-00004 07)
Affinity DataIC50: 7.5nMAssay Description:Inhibitors (initial concentration of 10 or 60 μM, three-fold serial dilutions) were incubated with IRE1α* in cleavage buffer (20 mM HEPES, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2024
Entry Details
US Patent