Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 11788
TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM648222(5-({(2S)-6-Amino-2-[4-(5-chloro-2-cyanophenyl)-5-m...)
Affinity DataIC50: 1.80nMAssay Description:Table A: Test substances are dissolved in dimethyl sulphoxide and serially diluted in dimethyl sulphoxide (3000 μM to 0.0078 μM; resulting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2024
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM648222(5-({(2S)-6-Amino-2-[4-(5-chloro-2-cyanophenyl)-5-m...)
Affinity DataIC50: 2.10nMAssay Description:Table A: Test substances are dissolved in dimethyl sulphoxide and serially diluted in dimethyl sulphoxide (3000 μM to 0.0078 μM; resulting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2024
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM648221(US11884660, Example 1 | 5-({6-Amino-2-[4-(5-chloro...)
Affinity DataIC50: 5.60nMAssay Description:Table A: Test substances are dissolved in dimethyl sulphoxide and serially diluted in dimethyl sulphoxide (3000 μM to 0.0078 μM; resulting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2024
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM648222(5-({(2S)-6-Amino-2-[4-(5-chloro-2-cyanophenyl)-5-m...)
Affinity DataIC50: 2.00E+3nMAssay Description:Table B: Test substances are dissolved in dimethyl sulphoxide and serially diluted in dimethyl sulphoxide (3000 μM to 0.0078 μM; resulting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2024
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM648222(5-({(2S)-6-Amino-2-[4-(5-chloro-2-cyanophenyl)-5-m...)
Affinity DataIC50: 2.00E+3nMAssay Description:Table B: Test substances are dissolved in dimethyl sulphoxide and serially diluted in dimethyl sulphoxide (3000 μM to 0.0078 μM; resulting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2024
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM648221(US11884660, Example 1 | 5-({6-Amino-2-[4-(5-chloro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Table B: Test substances are dissolved in dimethyl sulphoxide and serially diluted in dimethyl sulphoxide (3000 μM to 0.0078 μM; resulting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2024
Entry Details
US Patent