Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 11805
TargetBromodomain-containing protein 4(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM649470(US11890288, Compound 11)
Affinity DataIC50: 5.70nMAssay Description:The inhibitory action of the compound of the present invention on the binding of BRD4 protein and a ligand thereof (acetylated histone H4) was evalua...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM649469(US11890288, Compound 1)
Affinity DataIC50: 29nMAssay Description:The inhibitory action of the compound of the present invention on the binding of BRD4 protein and a ligand thereof (acetylated histone H4) was evalua...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM205429( (R)-JQ1 (3) | US9320741, (R)-JQ1 | US10407441, Co...)
Affinity DataIC50: 550nMAssay Description:The inhibitory action of the compound of the present invention on the binding of BRD4 protein and a ligand thereof (acetylated histone H4) was evalua...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent