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Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 11834
TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651963(US11903935, Compound IA-6)
Affinity DataIC50:  3.20E+3nMAssay Description:This assay is an adaptation of the NAD+/NADH Glo assay (Promega G9071). In this assay, NAD+ cycling enzymes convert NAD+ into NADH. In the presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM47032(2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl...)
Affinity DataIC50:  3.30E+3nMAssay Description:This assay is an adaptation of the NAD+/NADH Glo assay (Promega G9071). In this assay, NAD+ cycling enzymes convert NAD+ into NADH. In the presence o...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651963(US11903935, Compound IA-6)
Affinity DataIC50:  3.30E+3nMAssay Description:Reaction mixtures were prepared on ice by mixing 10 ul of SARM1 SAM-TIR cell lysate (320 fold dilution of lysate 11-3-2016, or 80 fold lysate dilutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM47032(2-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl...)
Affinity DataIC50:  3.50E+3nMAssay Description:Reaction mixtures were prepared on ice by mixing 10 ul of SARM1 SAM-TIR cell lysate (320 fold dilution of lysate 11-3-2016, or 80 fold lysate dilutio...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651968(US11903935, Compound IA-8)
Affinity DataIC50:  7.40E+3nMAssay Description:Reaction mixtures were prepared on ice by mixing 10 ul of SARM1 SAM-TIR cell lysate (320 fold dilution of lysate 11-3-2016, or 80 fold lysate dilutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651968(US11903935, Compound IA-8)
Affinity DataIC50:  8.70E+3nMAssay Description:This assay is an adaptation of the NAD+/NADH Glo assay (Promega G9071). In this assay, NAD+ cycling enzymes convert NAD+ into NADH. In the presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651962(US11903935, Compound IA-3)
Affinity DataIC50:  2.14E+4nMAssay Description:Reaction mixtures were prepared on ice by mixing 10 ul of SARM1 SAM-TIR cell lysate (320 fold dilution of lysate 11-3-2016, or 80 fold lysate dilutio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetNAD(+) hydrolase SARM1(Human)
Washington University

US Patent
LigandPNGBDBM651962(US11903935, Compound IA-3)
Affinity DataIC50:  2.83E+4nMAssay Description:This assay is an adaptation of the NAD+/NADH Glo assay (Promega G9071). In this assay, NAD+ cycling enzymes convert NAD+ into NADH. In the presence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent