Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 11859
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526882(CHEMBL4527232 | US11912678, Compound 2)
Affinity DataIC50: 108nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526883(CHEMBL4455001 | US11912678, Compound 7)
Affinity DataIC50: 158nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526881(CHEMBL4473326 | US11912678, Compound 6)
Affinity DataIC50: 190nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526878(CHEMBL4450247 | US11912678, Compound 3)
Affinity DataIC50: 293nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526883(CHEMBL4455001 | US11912678, Compound 7)
Affinity DataIC50: 308nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526887(CHEMBL4445322 | US11912678, Compound 4)
Affinity DataIC50: 332nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526879(CHEMBL4565316 | US11912678, Compound 1)
Affinity DataIC50: 360nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526882(CHEMBL4527232 | US11912678, Compound 2)
Affinity DataIC50: 368nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526881(CHEMBL4473326 | US11912678, Compound 6)
Affinity DataIC50: 426nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526889(CHEMBL4452771 | US11912678, Compound 8)
Affinity DataIC50: 474nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526887(CHEMBL4445322 | US11912678, Compound 4)
Affinity DataIC50: 523nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526879(CHEMBL4565316 | US11912678, Compound 1)
Affinity DataIC50: 696nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526890(CHEMBL4437566 | US11912678, Compound 5)
Affinity DataIC50: 777nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526878(CHEMBL4450247 | US11912678, Compound 3)
Affinity DataIC50: 1.06E+3nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM653909(N-(6-isopropylbenzothiazole-2-yl)-4-morpholinobenz...)
Affinity DataIC50: 1.17E+3nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526888(CHEMBL4543902 | US11912678, Compound 9)
Affinity DataIC50: 1.19E+3nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526889(CHEMBL4452771 | US11912678, Compound 8)
Affinity DataIC50: 1.38E+3nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM653909(N-(6-isopropylbenzothiazole-2-yl)-4-morpholinobenz...)
Affinity DataIC50: 1.95E+3nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50526888(CHEMBL4543902 | US11912678, Compound 9)
Affinity DataIC50: 4.00E+3nMAssay Description:The compounds were evaluated in LRRK2 and in the mutated form LRRK2 G2019S. This mutation is more frequent in the familial forms of Parkinson's D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
US Patent