Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 11917
TargetCytochrome P450 1A2(Human)
Wayne State University

US Patent
LigandPNGBDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 19.2nMAssay Description:A stock solution of KCI838 was be prepared in DMSO at 50 mM and stored at −20° C. Serial dilutions of the stock solution were prepared in aceto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetUDP-glucuronosyltransferase 1A1(Human)
Wayne State University

US Patent
LigandPNGBDBM13934(CGP 73547 | CHEMBL1163 | methyl N-[(1S)-1-{[(2S,3S...)
Affinity DataIC50: 792nMAssay Description:KCI838 was incubated at seven increasing concentrations with human UGT1A1-expressed Supersomes (0.25 mg/mL), alamethicin (25 μg/mL) and UDPGA (5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2024
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Wayne State University

US Patent
LigandPNGBDBM660588(US11938127, Compound KCI838)
Affinity DataIC50: 2.92E+3nMAssay Description:A stock solution of KCI838 was be prepared in DMSO at 50 mM and stored at −20° C. Serial dilutions of the stock solution were prepared in aceto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2024
Entry Details
US Patent

TargetUDP-glucuronosyltransferase 1A1(Human)
Wayne State University

US Patent
LigandPNGBDBM660588(US11938127, Compound KCI838)
Affinity DataIC50: 3.59E+4nMAssay Description:KCI838 was incubated at seven increasing concentrations with human UGT1A1-expressed Supersomes (0.25 mg/mL), alamethicin (25 μg/mL) and UDPGA (5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2024
Entry Details
US Patent