Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 11997
TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669432(US11964978, Example AIF11)
Affinity DataKi:  0.300nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669431(US11964978, Example AIF10)
Affinity DataKi:  1.30nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669428(US11964978, Example AIF07)
Affinity DataKi:  2nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669433(US11964978, Example AIF12)
Affinity DataKi:  2.40nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669452(US11964978, Example AIN04)
Affinity DataKi:  2.90nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669434(US11964978, Example AIF13)
Affinity DataKi:  2.90nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669418(US11964978, Example AIE01 | US11964978, Example AI...)
Affinity DataKi:  3.60nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669449(1-cyclopropyl-4-{4-[1-(3-methoxypropyl)-3-methyl-1...)
Affinity DataKi:  4.60nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669424(US11964978, Example AIF03)
Affinity DataKi:  5.70nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669416(US11964978, Example AIC03)
Affinity DataKi:  7.80nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669422(1-methyl-4-[1-methyl-4-(3-methyl-1-propyl-1H-pyraz...)
Affinity DataKi:  9.80nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669443(1-ethyl-4-{4-[1-(3-hydroxypropyl)-3-methyl-1H-pyra...)
Affinity DataKi:  10.2nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669409(4-[4-(1-ethyl-3-methyl-1H-pyrazol-5-yl)-1-methyl-1...)
Affinity DataKi:  10.7nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669420(US11964978, Example AIE03)
Affinity DataKi:  10.7nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669414(1-ethyl-4-[4-(1-ethyl-3-methyl-1H-pyrazol-5-yl)-1-...)
Affinity DataKi:  12.1nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669419(US11964978, Example AIE02)
Affinity DataKi:  12.7nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669451(US11964978, Example AIN03)
Affinity DataKi:  12.8nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669421(US11964978, Example AIE04)
Affinity DataKi:  13.7nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669445(4-{1-ethyl-4-[1-(3-methoxypropyl)-3-methyl-1H-pyra...)
Affinity DataKi:  15.2nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669410(US11964978, Example AIA02)
Affinity DataKi:  18nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669427(US11964978, Example AIF06)
Affinity DataKi:  18.2nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669450(US11964978, Example AIN02)
Affinity DataKi:  20.9nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669439(4-[4-(1,3-dimethyl-1H- pyrazol-5-yl)-1-methyl- 1H-...)
Affinity DataKi:  22.7nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669425(US11964978, Example AIF04)
Affinity DataKi:  23.6nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669446(4-(4-{1-[3-(difluoromethoxy)propyl]-3-methyl-1H-py...)
Affinity DataKi:  24.6nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669457(US11964978, Example AIP05)
Affinity DataKi:  27.1nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669435(US11964978, Example AIF14)
Affinity DataKi:  28.2nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669412(US11964978, Example AIA04)
Affinity DataKi:  33.8nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669456(US11964978, Example AIP04)
Affinity DataKi:  35.2nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669418(US11964978, Example AIE01 | US11964978, Example AI...)
Affinity DataKi:  39.7nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669453(4-{4-[1-(cyanomethyl)-3-methyl-1H-pyrazol-5-yl]-1-...)
Affinity DataKi:  43.1nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669436(US11964978, Example AIF15)
Affinity DataKi:  46.6nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669423(US11964978, Example AIF02)
Affinity DataKi:  54.6nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669458(4-{4-[1-(2-cyanoethyl)-3-methyl-1H-pyrazol-5-yl]-1...)
Affinity DataKi:  62.6nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669411(US11964978, Example AIA03)
Affinity DataKi:  71.4nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669437(4-[4-(1-ethyl-3-methyl-1H-pyrazol-5-yl)-1-methyl-1...)
Affinity DataKi:  81.8nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669417(4-(2-ethyl-1,4-dimethyl-1H-[1,4′-biimidazol]...)
Affinity DataKi:  87.5nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669442(4-[4-(1-ethyl-1H-pyrazol- 5-yl)-1-methyl-1H- imida...)
Affinity DataKi:  93.3nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669415(US11964978, Example AIC02)
Affinity DataKi:  113nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669448(US11964978, Example AIM02)
Affinity DataKi:  135nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669440(1-methyl-4-[1-methyl-4- (1-propyl-1H-pyrazol-5- yl...)
Affinity DataKi:  148nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669441(1-methyl-4-[1-methyl-4- (1-methyl-1H-pyrazol-5- yl...)
Affinity DataKi:  151nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669454(4-{4-[1-(2-amino-2-oxoethyl)-3-methyl-1H-pyrazol-5...)
Affinity DataKi:  161nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669447(1-methyl-4-[1-methyl-4-(3-methyl-1-{[(2R)-oxetan-2...)
Affinity DataKi:  175nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669413(4-[1-cyclopropyl-4-(1-ethyl-3-methyl-1H-pyrazol-5-...)
Affinity DataKi:  257nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669438(4-[4-(3-ethyl-1-methyl- 1H-pyrazol-4-yl)-1- methyl...)
Affinity DataKi:  352nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669455(US11964978, Example AIP03)
Affinity DataKi: >990nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669426(US11964978, Example AIF05)
Affinity DataKi: >990nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669430(US11964978, Example AIF09)
Affinity DataKi: >990nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM669429(US11964978, Example AIF08)
Affinity DataKi: >990nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent