Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 12246
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Suzhou Raymon Pharmaceuticals Company

US Patent
LigandPNGBDBM689543(US12054488, Compound I-1)
Affinity DataIC50: 10.7nMAssay Description:PI3-Kinase (human) HTRF Assay kit was used to detect the inhibition rate of the 6 compounds on PI3K-alpha enzyme at different concentrations, with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Suzhou Raymon Pharmaceuticals Company

US Patent
LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataIC50: 31.3nMAssay Description:PI3-Kinase (human) HTRF Assay kit was used to detect the inhibition rate of the 6 compounds on PI3K-alpha enzyme at different concentrations, with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Suzhou Raymon Pharmaceuticals Company

US Patent
LigandPNGBDBM689548(US12054488, Compound I-6)
Affinity DataIC50: 40.9nMAssay Description:PI3-Kinase (human) HTRF Assay kit was used to detect the inhibition rate of the 6 compounds on PI3K-alpha enzyme at different concentrations, with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Suzhou Raymon Pharmaceuticals Company

US Patent
LigandPNGBDBM689545(US12054488, Compound I-3)
Affinity DataIC50: 89.1nMAssay Description:PI3-Kinase (human) HTRF Assay kit was used to detect the inhibition rate of the 6 compounds on PI3K-alpha enzyme at different concentrations, with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Suzhou Raymon Pharmaceuticals Company

US Patent
LigandPNGBDBM689544(US12054488, Compound I-2)
Affinity DataIC50: 89.6nMAssay Description:PI3-Kinase (human) HTRF Assay kit was used to detect the inhibition rate of the 6 compounds on PI3K-alpha enzyme at different concentrations, with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Suzhou Raymon Pharmaceuticals Company

US Patent
LigandPNGBDBM689546(US12054488, Compound I-4)
Affinity DataIC50: 108nMAssay Description:PI3-Kinase (human) HTRF Assay kit was used to detect the inhibition rate of the 6 compounds on PI3K-alpha enzyme at different concentrations, with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Suzhou Raymon Pharmaceuticals Company

US Patent
LigandPNGBDBM689547(US12054488, Compound I-5)
Affinity DataIC50: 228nMAssay Description:PI3-Kinase (human) HTRF Assay kit was used to detect the inhibition rate of the 6 compounds on PI3K-alpha enzyme at different concentrations, with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent