Compile Data Set for Download or QSAR
Report error Found 746 Enz. Inhib. hit(s) with all data for entry = 12260
TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691028(US12065436, Compound 417 | (R)-N-(5-(5-ethylisoxaz...)
Affinity DataIC50: 600nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691231(US12065436, Compound 620 | (R)-3-chloro-N-(5-(5-et...)
Affinity DataIC50: 600nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691025((R)-N-(5-(5-ethylisoxazol-3-yl)-2,3- dihydro-1H-in...)
Affinity DataIC50: 600nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691035(US12065436, Compound 424 | (S)-N-(6-(5-ethylisoxaz...)
Affinity DataIC50: 600nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691175(US12065436, Compound 564 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 600nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690915(methyl (R)-(5-(5-ethyl-1,2,4- oxadiazol-3-yl)-2,3-...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691268(US12065436, Compound 657 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691264(US12065436, Compound 653 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691066(US12065436, Compound 455 | (S)-N-(6-(5-ethyl-1,2,4...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691020((R)-N-(5-(5-cyclobutyl-1,2,4- oxadiazol-3-yl)-2,3-...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690951((S)-N-(6-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691064(US12065436, Compound 453 | (S)-N-(6-(5-(difluorome...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690851((R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690997((R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690852((R)-N-(5-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690703((R)-N-(5-(5-(difluoromethyl)-1,2,4- oxadiazol-3-yl...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690864((R)-N-(5-(5-ethylisoxazol-3-yl)-2,3- dihydro-1H-in...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690956(methyl (R)-(5-(5-ethylisoxazol-3-yl)- 2,3-dihydro-...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691244(US12065436, Compound 633 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690839((S)-N-(6-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691177(US12065436, Compound 566 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691032(US12065436, Compound 421 | (S)-N-(6-(5-ethylisoxaz...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691042(US12065436, Compound 431 | (R)-N-(5-(5-ethylisoxaz...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691269(US12065436, Compound 658 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691044(US12065436, Compound 433 | (S)-N-(6-(5-ethylisoxaz...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690752((R)-N-(5-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690944(2,2-difluoroethyl (R)-(5-(5-ethyl- 1,2,4-oxadiazol...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690794((R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690726((R)-N-(5-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691059(US12065436, Compound 448 | (R)-N-(5-(5-(difluorome...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690802((S)-N-(6-(5-(difluoromethyl)-1,2,4- oxadiazol-3-yl...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690933(isobutyl (R)-(5-(5-ethyl-1,2,4- oxadiazol-3-yl)-2,...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691220(US12065436, Compound 609 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690735((S)-N-(6-(5-(difluoromethyl)-1,2,4- oxadiazol-3-yl...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691214((R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690704((R)-N-(5-(5-(difluoromethyl)-1,2,4- oxadiazol-3-yl...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690960(methyl (S)-(6-(5-ethyl-1,2,4- oxadiazol-3-yl)-2,3-...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691258(US12065436, Compound 647 | (R)-2-chloro-N-(5-(5-et...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690934(cyclopropylmethyl (R)-(5-(5-ethyl- 1,2,4-oxadiazol...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691288(US12065436, Compound 677 | (R)-N-(5-(5-(difluorome...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690754((R)-N-(5-(5-cyclobutyl-1,2,4- oxadiazol-3-yl)-2,3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691010((R)-N-(5-(5-cyclobutyl-1,2,4- oxadiazol-3-yl)-2,3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691173(US12065436, Compound 562 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690849((S)-N-(6-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691178(US12065436, Compound 567 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691239(US12065436, Compound 628 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691206(US12065436, Compound 595 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690868((R)-N-(5-(3-ethyl-1,2,4-oxadiazol-5- yl)-2,3-dihyd...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM691214((R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandPNGBDBM690833((S)-N-(6-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

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