Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 12320
TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695466(US12083115, Compound 8)
Affinity DataIC50: 1.00E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695463(US12083115, Compound 5)
Affinity DataIC50: 1.20E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695467(US12083115, Compound 9)
Affinity DataIC50: 1.40E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695465(US12083115, Compound 7)
Affinity DataIC50: 1.40E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695462(US12083115, Compound 4)
Affinity DataIC50: 1.50E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695381(US12083115, Compound 1)
Affinity DataIC50: 1.90E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695474(US12083115, Compound 16)
Affinity DataIC50: 2.40E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695481(US12083115, Compound 23)
Affinity DataIC50: 2.60E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695464(US12083115, Compound 6)
Affinity DataIC50: 2.80E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695471(US12083115, Compound 13)
Affinity DataIC50: 3.50E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695461(US12083115, Compound 3)
Affinity DataIC50: 4.14E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695468(US12083115, Compound 10)
Affinity DataIC50: 6.40E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695480(US12083115, Compound 22)
Affinity DataIC50: 9.60E+3nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695472(US12083115, Compound 14)
Affinity DataIC50: 1.04E+4nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695469(US12083115, Compound 11)
Affinity DataIC50: 1.49E+4nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695470(US12083115, Compound 12)
Affinity DataIC50: 2.03E+4nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695473(US12083115, Compound 15)
Affinity DataIC50: 2.67E+4nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695479(US12083115, Compound 21)
Affinity DataIC50: 5.06E+4nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM50593123(Venglustat | Genz-682452 | Gz402671 | Ibiglustat |...)
Affinity DataIC50: 6.01E+4nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695476(US12083115, Compound 18)
Affinity DataIC50: 1.48E+5nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695477(US12083115, Compound 19)
Affinity DataIC50: 1.70E+5nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695478(US12083115, Compound 20)
Affinity DataIC50: 3.60E+5nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetMannosyl-oligosaccharide glucosidase(Human)
Genzyme

US Patent
LigandPNGBDBM695475(US12083115, Compound 17)
Affinity DataIC50: 4.54E+5nMAssay Description:To determine glucosylceramide synthase inhibition, substrates at 2× of their Km (fluorescent ceramide and UDP-glucose, 3 μM and 4 μM respec...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent