Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 12326
LigandPNGBDBM695825(US12084442, Example 18 | 3-((8-Chloro-1-(2,6-dichl...)
Affinity DataIC50: 30nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695823(US12084442, Example 16 | 3-((8-Chloro-1-(2,6-dichl...)
Affinity DataIC50: 30nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695826(US12084442, Example 19 | N-(3-(8-Chloro-1-(2,6-dic...)
Affinity DataIC50: 50nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695827(US12084442, Example 20 | 8-Chloro-1-(2,6-dichloro-...)
Affinity DataIC50: 50nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695820(US12084442, Example 13 | (S)-3-((8-Chloro-1-(2,6-d...)
Affinity DataIC50: 60nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695812(US12084442, Example 5 | 2-((8-Chloro-1-(2,6-dichlo...)
Affinity DataIC50: 60nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695815(US12084442, Example 8 | (S)-3-((8-Chloro-1-(2,6-di...)
Affinity DataIC50: 70nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695814(US12084442, Example 7 | (R)-3-((8-Chloro-1-(2,6-di...)
Affinity DataIC50: 70nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695816(US12084442, Example 9 | N-(2-((8-chloro-1-(2,6-dic...)
Affinity DataIC50: 80nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695808(US12084442, Example 1 | 3-((8-Chloro-1-(2,6-dichlo...)
Affinity DataIC50: 90nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695813(US12084442, Example 6 | (R)-3-((8-Chloro-1-(2,6-di...)
Affinity DataIC50: 130nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695818(US12084442, Example 11 | 3-((8-Chloro-1-(2,6-dichl...)
Affinity DataIC50: 160nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695811(US12084442, Example 4 | 2-((8-Chloro-1-(2,6-dichlo...)
Affinity DataIC50: 160nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695821(US12084442, Example 14 | (S)-3-((8-chloro-1-(2,6-d...)
Affinity DataIC50: 170nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695828(US12084442, Example 21 | 8-Chloro-1-(2,6-dichloro-...)
Affinity DataIC50: 170nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695829(US12084442, Example 22 | 8-Chloro-1-(2,6-dichloro-...)
Affinity DataIC50: 190nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695819(US12084442, Example 12 | (R)-3-((8-Chloro-1-(2,6-d...)
Affinity DataIC50: 200nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695809(US12084442, Example 2 | 2-((8-Chloro-1-(2,6-dichlo...)
Affinity DataIC50: 220nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695810(US12084442, Example 3 | 3-((8-Chloro-1-(2,6-dichlo...)
Affinity DataIC50: 220nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695824(US12084442, Example 17 | 2-(4-(5-(2-Amino-2-oxoeth...)
Affinity DataIC50: 250nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695822(US12084442, Example 15 | 3-((8-Chloro-1-(2,6-dichl...)
Affinity DataIC50: 320nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

LigandPNGBDBM695817(US12084442, Example 10 | (S)-3-((8-Chloro-1-(2,6-d...)
Affinity DataIC50: 330nMAssay Description:The GIRK1/4 activity of a compound according to the present invention was assessed by the following in vitro method.Buffers:a. External buffer: 10 mM...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent