Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 12400
TargetCytochrome P450 2C9(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700732(N-(3-cyano-4-fluorophenyl)-1,2,4-trimethyl-5-(2-ox...)
Affinity DataIC50: 1.66E+4nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700732(N-(3-cyano-4-fluorophenyl)-1,2,4-trimethyl-5-(2-ox...)
Affinity DataIC50: 2.49E+4nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700728(BDBM700731 | (S)—N-(3-cyano-4-fluorophenyl)-1,2,4-...)
Affinity DataIC50: 4.64E+4nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700728(BDBM700731 | (S)—N-(3-cyano-4-fluorophenyl)-1,2,4-...)
Affinity DataIC50: 6.00E+4nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent

TargetCytochrome P450 2B6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700732(N-(3-cyano-4-fluorophenyl)-1,2,4-trimethyl-5-(2-ox...)
Affinity DataIC50: 6.11E+4nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700732(N-(3-cyano-4-fluorophenyl)-1,2,4-trimethyl-5-(2-ox...)
Affinity DataIC50: 7.60E+4nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700728(BDBM700731 | (S)—N-(3-cyano-4-fluorophenyl)-1,2,4-...)
Affinity DataIC50: 7.97E+4nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700732(N-(3-cyano-4-fluorophenyl)-1,2,4-trimethyl-5-(2-ox...)
Affinity DataIC50: 1.20E+5nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent

TargetCytochrome P450 2B6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700728(BDBM700731 | (S)—N-(3-cyano-4-fluorophenyl)-1,2,4-...)
Affinity DataIC50: 1.46E+5nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700728(BDBM700731 | (S)—N-(3-cyano-4-fluorophenyl)-1,2,4-...)
Affinity DataIC50: 2.00E+5nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700728(BDBM700731 | (S)—N-(3-cyano-4-fluorophenyl)-1,2,4-...)
Affinity DataIC50: 2.24E+5nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM700732(N-(3-cyano-4-fluorophenyl)-1,2,4-trimethyl-5-(2-ox...)
Affinity DataIC50: 2.29E+5nMAssay Description:500 μL of a final incubation system contains 50 μL of liver microsomes (protein concentration: 0.2 mg/mL), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2025
Entry Details
US Patent