Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 12595
TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712709((R)-8-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 6.30nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50561738(CHEMBL4793969 | US12195470, Example 49)
Affinity DataIC50: 6.60nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50561734(CHEMBL4782495 | US12195470, Example 3)
Affinity DataIC50: 8.10nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50561739(CHEMBL4741478 | US12195470, Example 55)
Affinity DataIC50: 8.10nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50561736(CHEMBL4750933 | US12195470, Example 41)
Affinity DataIC50: 9.90nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50561737(CHEMBL4788632 | US12195470, Example 45)
Affinity DataIC50: 10.3nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712754((R)—N-((1R,5S,8s)-3-(6-methylpyrimidin-4-yl)-3-aza...)
Affinity DataIC50: 10.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712711((R)-8-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 10.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712750((R)-8-(3,4-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 11.3nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712713((R)—N-((1R,5S,8s)-3-(6-methoxypyridazin-4-yl)-3-az...)
Affinity DataIC50: 11.3nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712708((R)—N-((1R,5S,8s)-3-(6-methoxypyridazin-4-yl)-3-az...)
Affinity DataIC50: 11.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712745((R)-7-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 11.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712722((R)-8-(3-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methoxy...)
Affinity DataIC50: 11.9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712741((R)-8-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 12.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712703((R)-7-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 12.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712758((R)—N-((1R,5S,8s)-3-(6-methylpyrimidin-4-yl)-3-aza...)
Affinity DataIC50: 13.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712760((R)-9-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 13.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712730((R)-8-(2-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 13.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712737((R)-7-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 15.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712724((R)-8-(2-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methoxy...)
Affinity DataIC50: 15.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712734((R)-7-(3,5-dichlorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 16nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712726((R)-7-(4-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 16.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712732((R)-8-(2,3-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 17.1nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712728((R)-7-(3-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 17.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712749((R)—N-((1R,5S,8s)-3-(6-methylpyrimidin-4-yl)-3-aza...)
Affinity DataIC50: 17.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712715((R)-8-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 19.9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712748((R)-8-(3,5-dichlorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 20nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712736((R)-8-(2,4-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 21.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712735((R)-7-(3,5-dichlorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 22.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712740((R)-8-(3-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 27.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712746((R)-7-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 27.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712744((R)-8-(4-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 28.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712753((R)-8-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 29.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712720((R)-8-(2,3-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 31.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712731((R)-8-(2-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 33.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712725((R)-8-(2-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methoxy...)
Affinity DataIC50: 33.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712742((R)-8-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 34nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50561735(CHEMBL4793879 | US12195470, Example 8)
Affinity DataIC50: 34.1nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712761((R)-9-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 34.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712717((R)-8-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 35.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712719((R)-8-(2,4-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 36.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712712((R)-8-(3,5-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 39.3nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712707((R)-7-(3-chloro-5-fluorophenoxy)-N-((1R,5S,8s)-3-(...)
Affinity DataIC50: 41.3nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712751((R)-8-(3,4-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 41.3nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712756((R)-9-(4-fluorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 42.8nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712755((R)—N-((1R,5S,8s)-3-(6-methylpyrimidin-4-yl)-3-aza...)
Affinity DataIC50: 43.2nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712718((R)—N-((1R,5S,8s)-3-(6-methylpyridazin-4-yl)-3-aza...)
Affinity DataIC50: 49.7nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712729((R)-7-(3-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methylp...)
Affinity DataIC50: 51.9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712733((R)-8-(2,3-difluorophenoxy)-N-((1R,5S,8s)-3-(6-met...)
Affinity DataIC50: 53.6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetAmyloid-beta precursor protein [1-42](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM712723((R)-8-(3-chlorophenoxy)-N-((1R,5S,8s)-3-(6-methoxy...)
Affinity DataIC50: 57.5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μL in 96-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

Displayed 1 to 50 (of 58 total ) | Next | Last >>
Jump to: