Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 12612
TargetProtein tyrosine phosphatase type IVA 1 (PTP4A1)(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 396097BDBM396097(US10308663, JMS-631-053 | US12227515, Compound JMS...)
Affinity DataIC50: 29.1nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713968BDBM713968(US12202839, Compound NRT-892-04)
Affinity DataIC50: 32.2nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 396097BDBM396097(US10308663, JMS-631-053 | US12227515, Compound JMS...)
Affinity DataIC50: 34.7nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 396097BDBM396097(US10308663, JMS-631-053 | US12227515, Compound JMS...)
Affinity DataIC50: 34.7nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713962BDBM713962(US12202839, Compound 9k)
Affinity DataIC50: 36.1nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713962BDBM713962(US12202839, Compound 9k)
Affinity DataIC50: 36.1nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713957BDBM713957(US12202839, Compound 9f)
Affinity DataIC50: 39.1nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713953BDBM713953(US12202839, Compound 9b)
Affinity DataIC50: 41.9nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 1 (PTP4A1)(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713966BDBM713966(US12202839, Compound 9o)
Affinity DataIC50: 43.2nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713964BDBM713964(US12202839, Compound 9m)
Affinity DataIC50: 47.4nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713961BDBM713961(US12202839, Compound 9j)
Affinity DataIC50: 47.6nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 2 (PTP4A2)(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 396097BDBM396097(US10308663, JMS-631-053 | US12227515, Compound JMS...)
Affinity DataIC50: 48nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713969BDBM713969(US12202839, Compound 9p)
Affinity DataIC50: 48.9nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 1 (PTP4A1)(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713962BDBM713962(US12202839, Compound 9k)
Affinity DataIC50: 49nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50535759BDBM50535759(CHEMBL4471843 | US12227515, Compound 3)
Affinity DataIC50: 49.5nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713963BDBM713963(US12202839, Compound 9l)
Affinity DataIC50: 53.4nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713960BDBM713960(US12202839, Compound 9i)
Affinity DataIC50: 53.4nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713952BDBM713952(US12202839, Compound 9a)
Affinity DataIC50: 61.7nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713954BDBM713954(US12227515, Compound 9a)
Affinity DataIC50: 62.5nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713959BDBM713959(US12202839, Compound 9h)
Affinity DataIC50: 65.7nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713965BDBM713965(US12202839, Compound 9n)
Affinity DataIC50: 67.7nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713955BDBM713955(US12202839, Compound 9d)
Affinity DataIC50: 71nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 2 (PTP4A2)(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713966BDBM713966(US12202839, Compound 9o)
Affinity DataIC50: 73.9nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713967BDBM713967(US12202839, Compound 9q)
Affinity DataIC50: 85.7nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713969BDBM713969(US12202839, Compound 9p)
Affinity DataIC50: 86nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713966BDBM713966(US12202839, Compound 9o)
Affinity DataIC50: 98.2nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713966BDBM713966(US12202839, Compound 9o)
Affinity DataIC50: 98.2nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50571230BDBM50571230(CHEMBL4862721 | US12227515, Compound EJR-887-35)
Affinity DataIC50: 107nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 2 (PTP4A2)(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713962BDBM713962(US12202839, Compound 9k)
Affinity DataIC50: 113nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 1 (PTP4A1)(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713969BDBM713969(US12202839, Compound 9p)
Affinity DataIC50: 133nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713951BDBM713951(US12202839, Compound 15)
Affinity DataIC50: 162nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713958BDBM713958(US12202839, Compound 9g)
Affinity DataIC50: 193nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50571225BDBM50571225(CHEMBL4862502 | US12227515, Compound EJR-887-24)
Affinity DataIC50: 206nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713956BDBM713956(US12202839, Compound 9e)
Affinity DataIC50: 256nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 2 (PTP4A2)(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 713969BDBM713969(US12202839, Compound 9p)
Affinity DataIC50: 264nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50571229BDBM50571229(CHEMBL4852178 | US12227515, Compound EJR-876-35)
Affinity DataIC50: 643nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 2 (PTP4A2)(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 396098BDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 396098BDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 1 (PTP4A1)(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 396098BDBM396098(US10308663, JMS-557-038 | US12227515, Compound JMS...)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 4: In Vitro Biochemical Analysis of PTP4A Inhibition. Enzyme activity assays were performed in triplicate in 384-well Greiner Bio-One black sma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent

TargetProtein tyrosine phosphatase type IVA 3(Human)
University of Virginia Patent Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50571227BDBM50571227(CHEMBL4854258 | US12227515, Compound EJR-876-34)
Affinity DataIC50: 4.98E+3nMAssay Description:Table 2: Recombinant human PTP4A3 phosphatase was used and the enzymatic assay was performed as previously described,20 except that it was fully auto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2025
Entry Details
US Patent