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Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 12671
TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719046BDBM719046(Preparation of N-(2-(1H-indol-3-yl)ethyl)-2-(5-chl...)
Affinity DataIC50: 63.1nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719045BDBM719045(N-(2-(1H-indol-3-yl)ethyl)-2-(5-methylpyridin-3-yl...)
Affinity DataIC50: 63.1nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719050BDBM719050(Preparation of N-(2-(6-fluoro-1H-indol-3-yl)ethyl)...)
Affinity DataIC50: 63.1nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719051BDBM719051(N-(2-(5-fluoro-1H-indol-3-yl)ethyl)-2-(5-fluoropyr...)
Affinity DataIC50: 79.4nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719025BDBM719025(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 100nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719033BDBM719033(1-(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropy...)
Affinity DataIC50: 100nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719027BDBM719027(N-(2-(1H-indol-3-yl)ethyl)-2-(pyridin-3-yl)-6,7-di...)
Affinity DataIC50: 158nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719020BDBM719020(5-(4-((2-(1H-indol-3-yl)ethyl)amino)-7-(cyanomethy...)
Affinity DataIC50: 158nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719042BDBM719042(Preparation of 5-(4-((2-(1H-indol-3-yl)ethyl)amino...)
Affinity DataIC50: 200nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719024BDBM719024(N-(2-(1H-indol-3-yl)ethyl)-2-(pyridin-3-yl)-5,6,7,...)
Affinity DataIC50: 200nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719048BDBM719048(Preparation of N-(2-(6-fluoro-1H-indol-3-yl)ethyl)...)
Affinity DataIC50: 200nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719026BDBM719026(N-(2-(1H-indol-3-yl)ethyl)-2-(pyridin-3-yl)-5,6,7,...)
Affinity DataIC50: 251nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719043BDBM719043(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 251nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719041BDBM719041(Preparation of N-(2-(1H-indol-3-yl)ethyl)-2-(5-chl...)
Affinity DataIC50: 316nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719023BDBM719023(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 316nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719049BDBM719049(Preparation of N-(2-(5-fluoro-1H-indol-3-yl)ethyl)...)
Affinity DataIC50: 316nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719028BDBM719028(4-(2-(1H-indol-3-yl)ethoxy)-2-(5-fluoropyridin-3-y...)
Affinity DataIC50: 398nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719040BDBM719040(Preparation of N-(2-(1H-indol-3-yl)ethyl)-2-(5-flu...)
Affinity DataIC50: 398nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719022BDBM719022(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 398nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719039BDBM719039(Preparation of N-(2-(1H-indol-3-yl)ethyl)-2-(5-met...)
Affinity DataIC50: 398nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719044BDBM719044(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 631nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719036BDBM719036(N-(2-(1H-indol-3-yl)ethyl)-7-benzyl-2-(5-fluoropyr...)
Affinity DataIC50: 631nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719034BDBM719034(US12221439, Example 17a)
Affinity DataIC50: 631nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719019BDBM719019(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 631nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719031BDBM719031(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropyrid...)
Affinity DataIC50: 794nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719029BDBM719029(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropyrid...)
Affinity DataIC50: 794nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719021BDBM719021(2-(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropy...)
Affinity DataIC50: 794nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719035BDBM719035(US12221439, Example 17b)
Affinity DataIC50: 794nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719018BDBM719018(1-(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropy...)
Affinity DataIC50: 1.00E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719032BDBM719032(Preparation of (4-((2-(1H-indol-3-yl)ethyl)amino)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719037BDBM719037(N-(2-(1H-indol-3-yl)ethyl)-2-(5-fluoropyridin-3-yl...)
Affinity DataIC50: 1.26E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719030BDBM719030(4-((2-(1H-indol-3-yl)ethyl)amino)-2-(5-fluoropyrid...)
Affinity DataIC50: 2.00E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719047BDBM719047(Preparation of N-(2-(1H-benzo[d]imidazol-2-yl)ethy...)
Affinity DataIC50: 3.16E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetCytochrome P450 1A1(Human)
Jaguahr Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 719038BDBM719038(Preparation of N-(2-(1H-benzo[d]imidazol-2-yl)ethy...)
Affinity DataIC50: 7.94E+3nMAssay Description:The direct CYP1A1 inhibitory activity of test compounds was also assessed using the Promega P450-Glo assay system. Seven concentrations of test compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent