Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 12824
TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585705(CHEMBL4856755 | US12281080, SCCP 6219)
Affinity DataIC50: 3.70nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585694(CHEMBL4878072 | US12281080, SCCP 6148)
Affinity DataIC50: 3.80nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM731283(US12281080, SCCP 6216)
Affinity DataIC50: 4.10nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585701(CHEMBL5080406 | US12281080, SCCP 6299)
Affinity DataIC50: 4.60nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM731287(US12281080, SCCP 6295)
Affinity DataIC50: 5.80nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585696(CHEMBL4851694 | US12281080, SCCP 6283)
Affinity DataIC50: 5.80nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585703(CHEMBL5094174 | US12281080, SCCP 6346)
Affinity DataIC50: 6.5nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585704(CHEMBL5077066 | US12281080, SCCP 6345)
Affinity DataIC50: 8.10nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585706(CHEMBL5087807 | US12281080, SCCP 6337)
Affinity DataIC50: 9.20nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585707(CHEMBL5091221 | US12281080, SCCP 6336)
Affinity DataIC50: 9.30nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585699(CHEMBL5094334 | US12281080, SCCP 6294)
Affinity DataIC50: 9.70nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585697(CHEMBL5086592 | US12281080, SCCP 6326)
Affinity DataIC50: 11.7nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM50585698(CHEMBL5083266 | US12281080, SCCP 6440)
Affinity DataIC50: 18.9nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent