Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 12907
TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738158BDBM738158(N-benzyl-2-(3-(pyridin-2-yl)-4-(quinolin-4-yl)-1H-...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 739530BDBM739530(N-(2,6-difluorobenzyl)-2-(3-(6-methylpyridin-2-yl)...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738220BDBM738220(N-(2-chlorobenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738218BDBM738218(N-(4-methylbenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738191BDBM738191(N-benzyl-2-(3-(6-methylpyridin-2-yl)-4-(quinolin-4...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738191BDBM738191(N-benzyl-2-(3-(6-methylpyridin-2-yl)-4-(quinolin-4...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 739651BDBM739651(N-(2-ethylbenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(q...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738218BDBM738218(N-(4-methylbenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738217BDBM738217(2-(3-(6-ethylpyridin-2-yl)-4-(quinolin-4-yl)-1H-py...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738216BDBM738216(N-benzyl-2-(3-(6-ethylpyridin-2-yl)-4-(quinolin-4-...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738212BDBM738212(N-(2-methylbenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 739652BDBM739652(N-(2,6-dichlorobenzyl)-2-(3-(6-methylpyridin-2-yl)...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 739651BDBM739651(N-(2-ethylbenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(q...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 739650BDBM739650(N-(2,6-dimethylbenzyl)-2-(3-(6-methylpyridin-2-yl)...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 739553BDBM739553(N-(2,6-dimethylbenzyl)-2-(3-(pyridin-2-yl)-4-(quin...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 739530BDBM739530(N-(2,6-difluorobenzyl)-2-(3-(6-methylpyridin-2-yl)...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738220BDBM738220(N-(2-chlorobenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(...)
Affinity DataIC50: 100nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738217BDBM738217(2-(3-(6-ethylpyridin-2-yl)-4-(quinolin-4-yl)-1H-py...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738212BDBM738212(N-(2-methylbenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738158BDBM738158(N-benzyl-2-(3-(pyridin-2-yl)-4-(quinolin-4-yl)-1H-...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 739653BDBM739653(4-((2-(3-(pyridin-2-yl)-4-(quinolin-4-yl)-1H-pyraz...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738199BDBM738199(N-(3-chlorobenzyl)-2-(3-(pyridin-2-yl)-4-(quinolin...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738198BDBM738198(N-(3-fluorobenzyl)-2-(3-(pyridin-2-yl)-4-(quinolin...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738192BDBM738192(N-(3-methylbenzyl)-2-(3-(pyridin-2-yl)-4-(quinolin...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738176BDBM738176(N-(4-methylbenzyl)-2-(3-(pyridin-2-yl)-4-(quinolin...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738173BDBM738173(N-(4-bromobenzyl)-2-(3-(pyridin-2-yl)-4-(quinolin-...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 739652BDBM739652(N-(2,6-dichlorobenzyl)-2-(3-(6-methylpyridin-2-yl)...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738162BDBM738162(N-(4-chlorobenzyl)-2-(3-(pyridin-2-yl)-4-(quinolin...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738160BDBM738160(N-(4-fluorobenzyl)-2-(3-(pyridin-2-yl)-4-(quinolin...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 739650BDBM739650(N-(2,6-dimethylbenzyl)-2-(3-(6-methylpyridin-2-yl)...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738215BDBM738215(N-(2-fluorobenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738214BDBM738214(N-(2-fluorobenzyl)-2-(3-(pyridin-2-yl)-4-(quinolin...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738211BDBM738211(N-(2-methylbenzyl)-2-(3-(pyridin-2-yl)-4-(quinolin...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738210BDBM738210(N-(3-cyanobenzyl)-2-(3-(pyridin-2-yl)-4-(quinolin-...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738224BDBM738224(N-(2,6-difluorobenzyl)-2-(3-(pyridin-2-yl)-4-(quin...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Agomab Spain, S.L.U.

US Patent
LigandChemical structure of BindingDB Monomer ID 738219BDBM738219(N-(2-chlorobenzyl)-2-(3-(pyridin-2-yl)-4-(quinolin...)
Affinity DataIC50: 450nMAssay Description:Human TGFβl R-1 inhibition experiments were carried out in a white 384-microplate low flange (Corning 3572) with ADP-Glo kinase Assay Kit (Promega V9...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent