Compile Data Set for Download or QSAR
Report error Found 171 Enz. Inhib. hit(s) with all data for entry = 13007
LigandChemical structure of BindingDB Monomer ID 750329BDBM750329(N-[4-[8-amino-5- chloro-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750327BDBM750327(N-[4-[8-amino-3- (trideuteriomethyl)- 5-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750326BDBM750326(N-[4-[8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750325BDBM750325(N-[4-[8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750323BDBM750323(N-[4-[8-amino-3- (trideuteriomethyl)- 5-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750338BDBM750338(N-[5-[8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750335BDBM750335(N-[5-[8-amino-6- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750334BDBM750334(N-(4-(8-amino- 3,5-dimethyl- imidazo[1,5-a] pyrazi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750333BDBM750333(N-(4-(8-amino- 3,5-dimethyl- imidazo[1,5-a] pyrazi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750331BDBM750331(N-[4-[8-amino-6- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750313BDBM750313(N-[4-[8-amino-3- (trideuteriomethyl)- 5-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750311BDBM750311(N-[4-[8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750310BDBM750310(N-[4-[8-amino-5- chloro-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750309BDBM750309(N-[4-[8-amino-5- chloro-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750307BDBM750307(N-[4-[8-amino-3- (trideuteriomethyl)- 5-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750322BDBM750322(N-[4-[8-amino-5- chloro-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750321BDBM750321(N-[4-[8-amino-5- chloro-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750320BDBM750320(N-[4-[8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750319BDBM750319(N-[4-[8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750317BDBM750317(N-[4-[8-amino-5- chloro-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750315BDBM750315(N-[4-[8-amino-6- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750346BDBM750346(N-[5-[8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750344BDBM750344(N-[5-[8-amino-6- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750341BDBM750341(N-[5-[8-amino-6- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750340BDBM750340(N-[5-[8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750339BDBM750339(N-[5-[8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750347BDBM750347(N-[5-[8-amino-6- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750178BDBM750178(N-(4-(8-amino-3- methylimidazo[1,5- a]pyrazin-1-yl...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750202BDBM750202(N-[4-[8-amino-5- chloro-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750201BDBM750201(N-[4-[8-amino-5- chloro-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750200BDBM750200(N-[4-[8-amino-3- (trideuteriomethyl)- 5-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750199BDBM750199(N-[4-[8-amino-3- (trideuteriomethyl)- 5-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750198BDBM750198(N-(4-(8-amino-5- chloro-3- methylimidazo[1,5- a]py...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750197BDBM750197(N-(4-(8-amino-5- chloro-3- methylimidazo[1,5- a]py...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750196BDBM750196(N-(4-(8-amino-3- methyl-5- (trifluoromethyl) imida...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750195BDBM750195(N-(4-(8-amino-3- methyl-5- (trifluoromethyl) imida...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750210BDBM750210(N-[4-[8-amino-3- (trideuteriomethyl)- 5-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750209BDBM750209(N-[4-[8-amino-3- (trideuteriomethyl)- 5-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750208BDBM750208(N-(4-(8-amino-3,5- dimethylimidazo [1,5-a]pyrazin-...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750207BDBM750207(N-(4-(8-amino-3,5- dimethylimidazo [1,5-a]pyrazin-...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750206BDBM750206(N-[4-[8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750205BDBM750205(N-[4-[8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750203BDBM750203(N-[4-[8-amino-6- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750186BDBM750186(N-(4-(8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750185BDBM750185(N-(4-(8-amino-5- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750183BDBM750183(N-(4-(8-amino-3,5- dimethylimidazo[1,5- a]pyrazin-...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750182BDBM750182(N-(4-(8-amino-6- methyl-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750180BDBM750180(N-(4-(8-amino-3,6- dimethylimidazo[1,5- a]pyrazin-...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750193BDBM750193(N-[4-[8-amino-3- (trideuteriomethyl)- 5-(trifluoro...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 750192BDBM750192(N-[4-[8-amino-5- chloro-3- (trideuteriomethyl) imi...)
Affinity DataIC50: 25nMAssay Description:In vitro Inhibition of PERK Enzyme Activity (isolated) Recombinant human EIF2AK2 (PKR) catalytic domain (amino acids 252-551), EIF2AK3 (PERK) catalyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
US Patent

Displayed 1 to 50 (of 171 total ) | Next | Last >>
Jump to: