Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 13178
TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 191570BDBM191570(US9670204, 12 2-((2-ethyl-8-fluoro-6-(4-(2-(3-hydr...)
Affinity DataIC50: 2nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50285777BDBM50285777(CHEMBL4165749 | BI-2545 (19))
Affinity DataIC50: 2.20nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50572920BDBM50572920(CHEMBL4877694 | US12391667, Example 1.3)
Affinity DataIC50: 2.20nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50572922BDBM50572922(CHEMBL4855996 | US12391667, Example 1.10)
Affinity DataIC50: 2.40nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50572918BDBM50572918(CHEMBL4867860 | US12391667, Example 1.1)
Affinity DataIC50: 2.5nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50572921BDBM50572921(CHEMBL4858728 | US12391667, Example 1.6)
Affinity DataIC50: 2.60nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50572919BDBM50572919(CHEMBL4867383 | US12391667, Example 1.2)
Affinity DataIC50: 3.40nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 50572923BDBM50572923(CHEMBL4851047 | US12391667, Example 1.13)
Affinity DataIC50: 3.40nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 765066BDBM765066(US12391667, Example 1.5)
Affinity DataIC50: 4.20nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 765069BDBM765069(US12391667, Example 1.8)
Affinity DataIC50: 4.20nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 765072BDBM765072(US12391667, Example 1.11)
Affinity DataIC50: 4.40nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 765073BDBM765073(US12391667, Example 1.12)
Affinity DataIC50: 4.80nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 719985BDBM719985(US20250051321, Compound GLPG1690 | WO2014139882, C...)
Affinity DataIC50: 5nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 765070BDBM765070(US12391667, Example 1.9)
Affinity DataIC50: 5.30nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 765065BDBM765065(US12391667, Example 1.4)
Affinity DataIC50: 5.80nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 765068BDBM765068(US12391667, Example 1.7)
Affinity DataIC50: 6.70nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2), 1 mM MgCl2 0.14 mM NaCl, and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent