Compile Data Set for Download or QSAR
Report error Found 134 Enz. Inhib. hit(s) with all data for entry = 13221
TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767642BDBM767642(6-chloro-7-fluoro-2-(5-fluoro- 4H-1,2,4-triazol-3-...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767641BDBM767641(1-(5-(6-chloro-7-fluoro-5- methoxy-3-(1H-pyrazol-4...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767606BDBM767606(ethyl 5-(6,7-dichloro-3-(1H- pyrazol-4-yl)-1H-indo...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767588BDBM767588(6-chloro-7-fluoro-2-(5-fluoro- 4H-1,2,4-triazol-3-...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767607BDBM767607(5-(6,7-dichloro-3-(1H-pyrazol- 4-yl)-1H-indol-2-yl...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767666BDBM767666(2-(5-(6-chloro-7-fluoro-5- methoxy-1-methyl-3-(1H-...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767663BDBM767663(1-(5-(6-chloro-7-fluoro-5- methoxy-3-(1H-pyrazol-4...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767594BDBM767594(6,7-dichloro-2-(5-(1,1- difluoro-2-methoxyethyl)-4...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767657BDBM767657(6-chloro-2-(5-(1,1-difluoro-2- methoxyethyl)-4H-1,...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767596BDBM767596(6,7-dichloro-3-(1H-pyrazol-4- yl)-2-(5-(trifluorom...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767592BDBM767592(1-(5-(6,7-dichloro-3-(1H- pyrazol-4-yl)-1H-indol-2...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767650BDBM767650(6-chloro-2-(5-(1,1-difluoro-2- methoxyethyl)-4H-1,...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767681BDBM767681(1-(5-(6-chloro-7-fluoro-3- (1H-imidazol-1-yl)-5- m...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767651BDBM767651(6-chloro-2-(5-(1,1- difluoroethyl)-4H-1,2,4- triaz...)
Affinity DataIC50: 30nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767649BDBM767649(6-chloro-2-(5-(1,1-difluoro-2- methoxyethyl)-4H-1,...)
Affinity DataIC50: 31nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767644BDBM767644(1-(5-(6-chloro-7-fluoro-5- methoxy-1-methyl-3-(1H-...)
Affinity DataIC50: 32nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767589BDBM767589(6-chloro-7-fluoro-5-methoxy- 3-(1H-pyrazol-4-yl)-2...)
Affinity DataIC50: 33nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767652BDBM767652(6-chloro-2-(5-(1,1- difluoroethyl)-4H-1,2,4- triaz...)
Affinity DataIC50: 33nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767683BDBM767683(1-(5-(6-chloro-7-fluoro-3- (1H-imidazol-1-yl)-5- m...)
Affinity DataIC50: 37nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767653BDBM767653(2-(5-(6-chloro-7-fluoro-5- methoxy-1-methyl-3-(1H-...)
Affinity DataIC50: 38nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767617BDBM767617(6-chloro-3-(1H-pyrazol-4-yl)- 2-(5-(trifluoromethy...)
Affinity DataIC50: 38nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767654BDBM767654(6-chloro-7-fluoro-2-(5-(1- fluoro-2-methoxyethyl)-...)
Affinity DataIC50: 39nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767664BDBM767664(1-(5-(6-chloro-7-fluoro-5- methoxy-1-methyl-3-(1H-...)
Affinity DataIC50: 39nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767674BDBM767674(6-chloro-2-(5-(1,1-difluoro-2- methoxyethyl)-4H-1,...)
Affinity DataIC50: 40nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767645BDBM767645(N-(5-(6-chloro-7-fluoro-5- methoxy-1-methyl-3-(1H-...)
Affinity DataIC50: 41nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767672BDBM767672(6-chloro-7-fluoro-2-(5-fluoro- 4H-1,2,4-triazol-3-...)
Affinity DataIC50: 43nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767655BDBM767655(6-chloro-7-fluoro-2-(5-(1- fluoroethyl)-4H-1,2,4-t...)
Affinity DataIC50: 44nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767601BDBM767601(6-chloro-7-fluoro-3-(1H- pyrazol-4-yl)-2-(5- (trif...)
Affinity DataIC50: 44nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767587BDBM767587(5-(6-chloro-7-fluoro-5- methoxy-1-methyl-3-(1H- py...)
Affinity DataIC50: 46nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767623BDBM767623(5-(6-chloro-7-fluoro-3-(1H- imidazol-1-yl)-5-metho...)
Affinity DataIC50: 48nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767597BDBM767597(6,7-dichloro-1-methyl-3-(1H- pyrazol-4-yl)-2-(5- (...)
Affinity DataIC50: 48nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767615BDBM767615(5-(6-chloro-5-methoxy-3-(1H- pyrazol-4-yl)-1H-indo...)
Affinity DataIC50: 49nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767648BDBM767648(1-(5-(6-chloro-7-fluoro-5- methoxy-1-methyl-3-(1H-...)
Affinity DataIC50: 52nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767647BDBM767647(2-((5-(6-chloro-7-fluoro-5- methoxy-1-methyl-3-(1H...)
Affinity DataIC50: 54nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767639BDBM767639(6-chloro-2-(5-(1,1-difluoro-2- methoxyethyl)-4H-1,...)
Affinity DataIC50: 55nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767640BDBM767640(6-chloro-7-fluoro-3-(1H- imidazol-1-yl)-5-methoxy-...)
Affinity DataIC50: 56nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767629BDBM767629((5-(6-chloro-7-fluoro-3-(1H- imidazol-1-yl)-5-meth...)
Affinity DataIC50: 56nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767680BDBM767680(2-(5-(6-chloro-7-fluoro-3- (1H-imidazol-1-yl)-5- m...)
Affinity DataIC50: 56nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767634BDBM767634(6-chloro-7-fluoro-3-(1H- imidazol-1-yl)-5-methoxy-...)
Affinity DataIC50: 57nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767628BDBM767628((5-(6-chloro-7-fluoro-3-(1H- imidazol-1-yl)-5-meth...)
Affinity DataIC50: 58nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767646BDBM767646(N-(5-(6-chloro-7-fluoro-5- methoxy-1-methyl-3-(1H-...)
Affinity DataIC50: 60nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767678BDBM767678(2-(5-(6-chloro-7-fluoro-3- (1H-imidazol-1-yl)-5- m...)
Affinity DataIC50: 60nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767625BDBM767625(5-(6-chloro-7-fluoro-3-(1H- imidazol-1-yl)-5-metho...)
Affinity DataIC50: 61nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767627BDBM767627((5-(6-chloro-7-fluoro-3-(1H- imidazol-1-yl)-5-meth...)
Affinity DataIC50: 61nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767656BDBM767656(6-chloro-7-fluoro-2-(5-(1- fluoroethyl)-4H-1,2,4-t...)
Affinity DataIC50: 61nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767626BDBM767626((5-(6-chloro-7-fluoro-3-(1H- imidazol-1-yl)-5-meth...)
Affinity DataIC50: 63nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767669BDBM767669((R)-1-(5-(6-chloro-7-fluoro-3- (1H-imidazol-1-yl)-...)
Affinity DataIC50: 63nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767667BDBM767667(1-(5-(6-chloro-7-fluoro-3- (1H-imidazol-1-yl)-5- m...)
Affinity DataIC50: 63nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767684BDBM767684(6-chloro-2-(5-(2,2-difluoro-1- methoxyethyl)-4H-1,...)
Affinity DataIC50: 64nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767685BDBM767685(2-(5-(1-(1H-imidazol-1-yl)-2- methoxyethyl)-4H-1,2...)
Affinity DataIC50: 65nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent

Displayed 1 to 50 (of 134 total ) | Next | Last >>
Jump to: