Compile Data Set for Download or QSAR
Report error Found 1490 Enz. Inhib. hit(s) with all data for entry = 13229
TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769283BDBM769283((5R)-5'-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methy...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769147BDBM769147((S)-5-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methyla...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769146BDBM769146(5-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazeti...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769294BDBM769294((3R)-6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769276BDBM769276(N-[(3R)-6-[7,7-difluoro-2-[(2S,3R)-3-fluoro-2-meth...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769086BDBM769086((5R)-5'-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methy...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769095BDBM769095(6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazeti...)
Affinity DataIC50: 0.100nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769271BDBM769271(N-[6-[7,7-difluoro-2-[(2S,3R)-3-fluoro-2-methyl-az...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769416BDBM769416(6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl-azet...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769290BDBM769290(6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl-azet...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769126BDBM769126(N-((R)-6-(7,7-difluoro-2-((S)-2-methylazetidin-1-y...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769084BDBM769084((S)-5'-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methyl...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769081BDBM769081((R)-6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methyla...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769286BDBM769286(6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl-azet...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769097BDBM769097((S)-6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methyla...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769074BDBM769074((S)-5-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methyla...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769159BDBM769159((S)-(5-(7,7-difluoro-2-((2S,3R)-3-fluoro-2-methyla...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769427BDBM769427((R)-6-(7,7-difluoro-2-((R)-2-(trifluoromethyl)azet...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769299BDBM769299((3S)-6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769157BDBM769157((3S)-6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methyl...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769161BDBM769161((S)-(5-(2-((S)-3,3-difluoro-2-methylazetidin-1-yl)...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769282BDBM769282((5R)-5'-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methy...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769156BDBM769156(6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazeti...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769297BDBM769297(6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl-azet...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769394BDBM769394(3-amino-3-(4-(7,7-difluoro-2-((2S,3R)-3-fluoro-2-m...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769273BDBM769273((5S)-5'-[7,7-difluoro-2-[(2R)-2-(fluoromethyl)azet...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769296BDBM769296(6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl-azet...)
Affinity DataIC50: 0.300nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769423BDBM769423((S)-6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methyla...)
Affinity DataIC50: 0.300nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769287BDBM769287(6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazeti...)
Affinity DataIC50: 0.300nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769160BDBM769160((S)-(5-(7,7-difluoro-2-((2S,3S)-3-fluoro-2-methyla...)
Affinity DataIC50: 0.300nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769235BDBM769235((S)-5-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methyla...)
Affinity DataIC50: 0.300nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769079BDBM769079(6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazeti...)
Affinity DataIC50: 0.300nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769272BDBM769272(N-[6-[7,7-difluoro-2-[(2S,3R)-3-fluoro-2-methyl-az...)
Affinity DataIC50: 0.300nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769137BDBM769137((S)-cyclopropyl(5-(7,7-difluoro-2-((2S,3R)-3-hydro...)
Affinity DataIC50: 0.400nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769185BDBM769185(3-[4-[7,7-difluoro-2-[(2R)-2-(trifluoromethyl)azet...)
Affinity DataIC50: 0.400nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769291BDBM769291(6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl-azet...)
Affinity DataIC50: 0.400nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769399BDBM769399((R)-3-amino-3-(4-(7,7-difluoro-2-(2-(trifluorometh...)
Affinity DataIC50: 0.400nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769300BDBM769300(6-[7,7-difluoro-2-[(2R)-2-(trifluoromethyl)azetidi...)
Affinity DataIC50: 0.400nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769075BDBM769075(N-(6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylaz...)
Affinity DataIC50: 0.400nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769229BDBM769229(N-((S)-5-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-meth...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769185BDBM769185(3-[4-[7,7-difluoro-2-[(2R)-2-(trifluoromethyl)azet...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769422BDBM769422((S)-(5-(7,7-difluoro-2-((R)-2-(trifluoromethyl)aze...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769278BDBM769278(N-[(3R)-6-[2-[(2S)-3,3-difluoro-2-methyl-azetidin-...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769400BDBM769400(3-amino-3-(4-(7,7-difluoro-2-((R)-2-(trifluorometh...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769355BDBM769355(N-[6-[7,7-difluoro-2-[(2S)-2-methylazetidin-1-yl]-...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 50628740BDBM50628740(CHEMBL5402865 | US12410160, Example 696)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769140BDBM769140((S)-(2-cyclopropoxy-5-(7,7-difluoro-2-((2S,3R)-3-h...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769064BDBM769064(N-((R)-6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-meth...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769233BDBM769233(5-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazeti...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 769292BDBM769292(6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl-azet...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

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