Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 13254
TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771455((3S)-6-chloro-2'-(5-chloro-2- fluorophenyl)-5'-(2...)
Affinity DataKi:  1.70nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771499((3S)-6-chloro-2'-(3-chloro-4- fluorophenyl)-5'-(2...)
Affinity DataKi:  1.70nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771518((3S)-6-chloro-2'-(5-chloro-2- fluorophenyl)-5'-[6...)
Affinity DataKi:  1.70nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771446((3S)-6-chloro-2'-(3- chlorophenyl)-5'-(2,4- dime...)
Affinity DataKi:  1.80nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771519((3S)-6-chloro-2'-(3,4- difluorophenyl)-5'-(2,4- ...)
Affinity DataKi:  1.90nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771521((3,S)-6-chloro-2'-(3,4- difluorophenyl)-5'-(4,6- ...)
Affinity DataKi:  1.90nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771522((3S)-6-chloro-2'-(5-chloro-2- fluorophenyl)-5'-(4...)
Affinity DataKi:  2nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771573((3S)-6-chloro-2'-(5-chloro-2,4- difluorophenyl)-5...)
Affinity DataKi:  2nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771500((3S)-6-chloro-2'-(5-chloro-2- fluorophenyl)-6'-(p...)
Affinity DataKi:  2.20nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771493((3S)-6-chloro-2'-(5-chloro-2- methylphenyl)-6'-(p...)
Affinity DataKi:  2.40nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-111](Human)
Adamed Pharma

US Patent
LigandPNGBDBM771574((3S)-6-(butan-2-yl)-6-chloro-2'- (5-chloro-2-fluo...)
Affinity DataKi:  2.5nMAssay Description:Fluorescence polarization experiments were read on Biotek Cytation 5 reader with the 470 nm excitation and 520 nm emission filters for fluorescein. T...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent