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Found
25
Enz. Inhib. hit(s) with all data for entry = 13255
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771581
(US12415816, Compound I-7)
Copy SMILES
Affinity Data
IC50: 550nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771599
(US12415816, Compound I-25)
Copy SMILES
Affinity Data
IC50: 630nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771582
(US12415816, Compound I-8)
Copy SMILES
Affinity Data
IC50: 639nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771579
(US12415816, Compound I-5)
Copy SMILES
Affinity Data
IC50: 660nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771593
(US12415816, Compound I-19)
Copy SMILES
Affinity Data
IC50: 824nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771578
(US12415816, Compound I-4)
Copy SMILES
Affinity Data
IC50: 881nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771592
(US12415816, Compound I-18)
Copy SMILES
Affinity Data
IC50: 1.45E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771580
(US12415816, Compound I-6)
Copy SMILES
Affinity Data
IC50: 1.45E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771594
(US12415816, Compound I-20)
Copy SMILES
Affinity Data
IC50: 2.83E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771597
(US12415816, Compound I-23)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771598
(US12415816, Compound I-24)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771575
(US12415816, Compound I-1)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771576
(US12415816, Compound I-2)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771577
(US12415816, Compound I-3)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771583
(US12415816, Compound I-9)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771584
(US12415816, Compound I-10)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771585
(US12415816, Compound I-11)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771586
(US12415816, Compound I-12)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771587
(US12415816, Compound I-13)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771588
(US12415816, Compound I-14)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771589
(US12415816, Compound I-15)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771590
(US12415816, Compound I-16)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771591
(US12415816, Compound I-17)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771595
(US12415816, Compound I-21)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Tyrosine-protein kinase JAK2
(Human)
Dana-Farber Cancer Institute
US Patent
Ligand
BDBM771596
(US12415816, Compound I-22)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL